Chemical Constituents of Salix babylonica L. and Their Antibacterial Activity Against Gram-Positive and Gram-Negative Animal Bacteria
| العنوان: | Chemical Constituents of Salix babylonica L. and Their Antibacterial Activity Against Gram-Positive and Gram-Negative Animal Bacteria |
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| المؤلفون: | Deyanira Ojeda-Ramírez, Manasés González-Cortazar, Adrian Zaragoza-Bastida, Camelia Alejandra Herrera-Corredor, Nallely Rivero-Perez, Marco Rivas-Jacobo, Benjamín Valladares-Carranza, Eddy Nathalye González-Alamilla |
| المصدر: | Molecules Volume 24 Issue 16 Molecules, Vol 24, Iss 16, p 2992 (2019) |
| بيانات النشر: | MDPI AG, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Staphylococcus aureus, Microorganism, Pharmaceutical Science, Salix babylonica L. hydroalcoholic extract, Microbial Sensitivity Tests, medicine.disease_cause, Article, Analytical Chemistry, lcsh:QD241-441, 03 medical and health sciences, chemistry.chemical_compound, Salix babylonica, lcsh:Organic chemistry, antibacterial activity, Listeria monocytogenes, Drug Discovery, Escherichia coli, medicine, Food science, luteolin, Physical and Theoretical Chemistry, Chromatography, High Pressure Liquid, 030304 developmental biology, Flavonoids, 0303 health sciences, Ethanol, biology, Plant Extracts, 030306 microbiology, Organic Chemistry, Water, Salix, luteoloside, biology.organism_classification, Anti-Bacterial Agents, chemistry, Chemistry (miscellaneous), Solvents, Molecular Medicine, Antibacterial activity, Luteolin, Bacteria |
| الوصف: | The principle of animal wellbeing, which states that animals should be free from pain, injury, and disease, is difficult to maintain, because microorganisms are most frequently found to be resistant or multi-resistant to drugs. The secondary metabolites of plants are an alternative for the treatment of these microorganisms. The aim of this work was to determine the antibacterial effect of Salix babylonica L. hydroalcoholic extract (SBHE) against Escherichia coli, Staphylococcus aureus and Listeria monocytogenes, and identify the compounds associated with the activity. The SBHE showed activity against the three strains, and was subjected to a bipartition, obtaining aqueous fraction (ASB) with moderate activity and organic fraction (ACSB) with good activity against the three strains. The chromatographic separation of ACSB, allowed us to obtain ten fractions (F1AC to F10AC), and only three showed activity (F7AC, F8AC and F10AC). In F7AC, five compounds were identified preliminary by GC-MS, in F8AC and F10AC were identified luteolin (1) and luteolin 7-O-glucoside (2) by HPLC, respectively. The best antibacterial activity was obtained with F7AC (Listeria monocytogenes MIC: 0.78 mg/mL, MBC: 0.78 mg/mL) and F8AC (Staphylococcus aureus MIC: 0.39 mg/mL MBC: 0.78 mg/mL). The results indicated that the compounds obtained from SBHE can be used as an alternative treatment against these microorganisms and, by this mechanism, contribute to animal and human health. |
| وصف الملف: | application/pdf |
| تدمد: | 1420-3049 |
| DOI: | 10.3390/molecules24162992 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c8d7c2127e5e80fb96ea1c21092881 https://doi.org/10.3390/molecules24162992 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....a0c8d7c2127e5e80fb96ea1c21092881 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14203049 |
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| DOI: | 10.3390/molecules24162992 |