Associations Between At-Risk Alcohol Use, Substance Use, and Smoking with Lipohypertrophy and Lipoatrophy Among Patients Living with HIV
| العنوان: | Associations Between At-Risk Alcohol Use, Substance Use, and Smoking with Lipohypertrophy and Lipoatrophy Among Patients Living with HIV |
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| المؤلفون: | Marisela Noorhasan, Daniel R. Drozd, Carl Grunfeld, Joseph O. Merrill, Greer A. Burkholder, Michael J. Mugavero, James H. Willig, Amanda L. Willig, Karen L. Cropsey, Kenneth H. Mayer, Aaron Blashill, Matthew Mimiaga, Mary E. McCaul, Heidi Hutton, Geetanjali Chander, William C. Mathews, Sonia Napravnik, Joseph J. Eron, Katerina Christopoulos, Rob J. Fredericksen, Robin M. Nance, Joseph Chris Delaney, Paul K. Crane, Michael S. Saag, Mari M. Kitahata, Heidi M. Crane, null on behalf of the Centers For AIDS R |
| المصدر: | AIDS research and human retroviruses, vol 33, iss 6 |
| بيانات النشر: | Mary Ann Liebert Inc, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | 0301 basic medicine, medicine.medical_specialty, Epidemiology, Clinical Sciences, Immunology, Human immunodeficiency virus (HIV), physical activity, substance use, Alcohol, medicine.disease_cause, Substance Misuse, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Clinical Research, Virology, Internal medicine, medicine, 030212 general & internal medicine, lipohypertrophy, Psychiatry, Lipoatrophy, Generalized estimating equation, lipoatrophy, business.industry, Prevention, Lipohypertrophy, alcohol use, medicine.disease, 030112 virology, Physical activity level, Good Health and Well Being, Infectious Diseases, chemistry, Cohort, HIV/AIDS, Drug Abuse (NIDA only), business, Viral load |
| الوصف: | ObjectiveTo examine associations between lipohypertrophy and lipoatrophy and illicit drug use, smoking, and at-risk alcohol use among a large diverse cohort of persons living with HIV (PLWH) in clinical care.Methods7,931 PLWH at six sites across the United States completed 21,279 clinical assessments, including lipohypertrophy and lipoatrophy, drug/alcohol use, physical activity level, and smoking. Lipohypertrophy and lipoatrophy were measured using the FRAM body morphology instrument and associations were assessed with generalized estimating equations.ResultsLipohypertrophy (33% mild, 4% moderate-to-severe) and lipoatrophy (20% mild, 3% moderate-to-severe) were common. Older age, male sex, and higher current CD4 count were associated with more severe lipohypertrophy (p values |
| وصف الملف: | application/pdf |
| تدمد: | 1931-8405 0889-2229 |
| DOI: | 10.1089/aid.2015.0357 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a080296e9241af541162d6bf46cbb2c1 https://doi.org/10.1089/aid.2015.0357 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....a080296e9241af541162d6bf46cbb2c1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19318405 08892229 |
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| DOI: | 10.1089/aid.2015.0357 |