Characterization of sustained-release chitosan film loaded with rutin-β-cyclodextrin complex and glucoamylase
| العنوان: | Characterization of sustained-release chitosan film loaded with rutin-β-cyclodextrin complex and glucoamylase |
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| المؤلفون: | Lijun Jiang, Chengye Ma, Dongliang Zhang, Hongjun Li, Jinhuan Zong, Shanfeng Chen |
| المصدر: | J Food Sci Technol |
| بيانات النشر: | Springer Science and Business Media LLC, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Antioxidant, Scanning electron microscope, medicine.medical_treatment, macromolecular substances, 02 engineering and technology, law.invention, Chitosan, Rutin, chemistry.chemical_compound, Hydrolysis, 0404 agricultural biotechnology, Magazine, law, medicine, chemistry.chemical_classification, Cyclodextrin, technology, industry, and agriculture, 04 agricultural and veterinary sciences, 021001 nanoscience & nanotechnology, 040401 food science, carbohydrates (lipids), chemistry, Reagent, Original Article, 0210 nano-technology, Food Science, Nuclear chemistry |
| الوصف: | Edible chitosan film incorporated with rutin-β-cyclodextrin was developed and characterized. The delivery of rutin was improved via the hydrolyzation function of glucoamylase, and the antioxidant activity of the chitosan film was enhanced by the addition of rutin. Sodium bicarbonate solution at different pHs (pH-adjusting reagent) was employed to afford the mild condition for the incorporated glucoamylase. The enzyme exhibited its hydrolyzation function to improve the release rate of rutin by destabilizing the rutin-β-cyclodextrin complex (RCC) in chitosan film. The optimum pH of glucoamylase was achieved with 5 mL addition amount of 0.5 mol/L sodium bicarbonate solution, and the glucoamylase improved the radical scavenging ratio of chitosan film. The yellowness of chitosan film was enhanced with the addition of RCC solution. The films prepared without water demonstrated coarse and rough surface, while the water-based films had smoother and even surface as examined by scanning electron microscopy. In contrast, these observations disappeared in the water immersion groups. X-ray diffraction suggested that the hydrolyzation of β-cyclodextrin and the interlinkage between β-cyclodextrin and the chitosan chain exerted a negative function on maintaining the crystal structure of pure chitosan film. Further, the destabilization of RCC complex with the glucoamylase activity was evidenced by the absence of peak associated with β-cyclodextrin as observed from Fourier transform infrared spectra. The enzyme improved the release of rutin and the addition of RCC successfully endowed antioxidant activity to the chitosan film. GRAPHIC ABSTRACT: [Image: see text] |
| تدمد: | 0975-8402 0022-1155 |
| DOI: | 10.1007/s13197-019-04106-9 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f4ffc5c1eabe463ffd9775ea4712038 https://doi.org/10.1007/s13197-019-04106-9 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....9f4ffc5c1eabe463ffd9775ea4712038 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 09758402 00221155 |
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| DOI: | 10.1007/s13197-019-04106-9 |