Variables associated with use of symptomatic medication during a headache attack in individuals with tension-type headache:a European study
| العنوان: | Variables associated with use of symptomatic medication during a headache attack in individuals with tension-type headache:a European study |
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| المؤلفون: | César Fernández-de-las-Peñas, Guerrero-Peral Ál, Lars Arendt-Nielsen, Matteo Castaldo, Antonella Catena, Kelun Wang, María Palacios-Ceña |
| المصدر: | Fernández-de-Las-Peñas, C, Palacios-Ceña, M, Castaldo, M, Wang, K, Guerrero-Peral, Á, Catena, A & Arendt-Nielsen, L 2020, ' Variables associated with use of symptomatic medication during a headache attack in individuals with tension-type headache : a European study ', BMC Neurology, vol. 20, no. 1, 43 . https://doi.org/10.1186/s12883-020-1624-8 BMC Neurology, Vol 20, Iss 1, Pp 1-10 (2020) BMC Neurology |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Adult, Male, Pain Threshold, medicine.medical_specialty, Neurology, Tension type headache, Pressure pain, Hospital Anxiety and Depression Scale, Sensitization, lcsh:RC346-429, Pittsburgh Sleep Quality Index, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Humans, Neurochemistry, Longitudinal Studies, 030212 general & internal medicine, lcsh:Neurology. Diseases of the nervous system, Depression (differential diagnoses), Analgesics, business.industry, Tension-Type Headache, General Medicine, Middle Aged, Europe, Medication intake, Anxiety, Female, Observational study, Neurology (clinical), Neurosurgery, medicine.symptom, business, 030217 neurology & neurosurgery, Research Article |
| الوصف: | Background Pharmacological treatment of patients with tension-type headache (TTH) includes symptomatic (acute) and prophylactic (preventive) medication. No previous study has investigated variables associated to symptomatic medication intake in TTH. Our aim was to assess the association of clinical, psychological and neurophysiological outcomes with the use and timing of the use of symptomatic medication in TTH. Methods A longitudinal observational study was conducted. One hundred and sixty-eight (n = 168) patients with TTH participated. Pain features of the headache (intensity, frequency, duration), burden of headache (Headache Disability Inventory), sleep quality (Pittsburgh Sleep Quality Index), anxiety/depression (Hospital Anxiety and Depression Scale), trait/state anxiety levels (State-Trait Anxiety Inventory), and bilateral pressure pain thresholds on the temporalis, C5-C6 joint, second metacarpal and tibialis anterior were assessed. Symptomatic medication intake was also collected for a 6-months follow-up period. Differences between patients using or not using symptomatic medication, depending on self-perceived effectiveness, and time (early during an attack, i.e., the first 5 min, or when headache attack is intense) when the symptomatic medication was taken were calculated. Results One hundred and thirty-six (n = 136, 80%) reported symptomatic medication intake for headache (73% NSAIDs). Sixteen (12%) reported no pain relief, 81 (59%) experienced moderate relief and 39 (29%) total pain relief. Fifty-eight (43%) took ‘early medication’ whereas 78 (57%) took ‘late medication’. Patients taking symptomatic medication in general showed lower headache frequency and lower depressive levels than those patients not taking medication. Symptomatic medication was more effective in patients with lower headache history, frequency, and duration, and lower emotional burden. No differences in pressure pain sensitivity were found depending on the self-perceived effectiveness of medication. Patients taking ‘late symptomatic’ medication exhibited more widespread pressure pain sensitivity than those taking ‘early medication’. Conclusions This study found that the effectiveness of symptomatic medication was associated with better headache parameters (history, frequency, or duration) and lower emotional burden. Further, consuming early symptomatic medication at the beginning of a headache attack (the first 5 min) could limit widespread pressure pain sensitivity. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| DOI: | 10.1186/s12883-020-1624-8 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea3542336e63976b8803a75799c4150 https://vbn.aau.dk/da/publications/69bdacc2-f55f-4e4c-b073-415dd466d844 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....9ea3542336e63976b8803a75799c4150 |
| قاعدة البيانات: | OpenAIRE |
| DOI: | 10.1186/s12883-020-1624-8 |
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