The Clinical Radiographic Incidence of Posttraumatic Osteoarthritis 10 Years After Anterior Cruciate Ligament Reconstruction: Data From the MOON Nested Cohort
| العنوان: | The Clinical Radiographic Incidence of Posttraumatic Osteoarthritis 10 Years After Anterior Cruciate Ligament Reconstruction: Data From the MOON Nested Cohort |
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| المؤلفون: | Carl S. Winalski, Charles L Cox, Jack T. Andrish, Rosemary A Sanders, Morgan H. Jones, Emily K. Reinke, Nancy A. Obuchowski, Angela D Pedroza, Laura J. Huston, Richard D. Parker, David C. Flanigan, Christopher C. Kaeding, Robert A. Magnussen, Kurt P. Spindler, Sercan Yalcin, Josh S Everhart |
| المصدر: | Am J Sports Med |
| بيانات النشر: | SAGE Publications, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | musculoskeletal diseases, medicine.medical_specialty, Joint space narrowing, Knee Joint, Anterior cruciate ligament reconstruction, medicine.medical_treatment, Radiography, Anterior cruciate ligament, Physical Therapy, Sports Therapy and Rehabilitation, Osteoarthritis, Article, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Orthopedics and Sports Medicine, Prospective Studies, Grading (tumors), Aged, 030222 orthopedics, Anterior Cruciate Ligament Reconstruction, business.industry, Anterior Cruciate Ligament Injuries, Incidence, Incidence (epidemiology), Reproducibility of Results, 030229 sport sciences, Osteoarthritis, Knee, musculoskeletal system, medicine.disease, Surgery, Orthopedics, medicine.anatomical_structure, Cohort, business |
| الوصف: | Background: The incidence of posttraumatic osteoarthritis (PTOA) based on clinical radiographic grading criteria at 10 years after anterior cruciate ligament (ACL) reconstruction (ACLR) has not been well-defined in a prospective cohort of young athletic patients. Hypothesis: Among young athletic patients, there is a high incidence of clinical radiographic PTOA at 10 years after ACLR. Additionally, there is a significant difference in clinical radiographic osteoarthritis (OA) changes (joint space narrowing and osteophyte formation) between ACL-reconstructed and contralateral knees at 10 years. Study Design: Case series; Level of evidence, 4. Methods: The first 146 patients in an ongoing nested cohort study of the Multicenter Orthopaedic Outcomes Network (MOON) prospective cohort presented for a minimum 10-year follow-up. Included patients had a sports-related ACL injury, were aged Results: Interrater reliability was substantial for the IKDC (Gwet Agreement Coefficient [AC] 1 = 0.71), moderate for the KL (0.48), and almost perfect for the OARSI (0.84) grading systems. Among patients with a contralateral radiographically normal knee, the 10-year incidence of clinical radiographic PTOA after ACLR was 37% as defined by osteophytes and 23% as defined by joint space narrowing. The maximum side-to-side difference in the OARSI osteophyte grade in the medial or lateral compartment was 0 in 65% of patients, 1 in 20%, and ≥2 in 15%. The maximum side-to-side difference in the OARSI joint space narrowing grade was 0 in 77% of patients, 1 in 19%, and ≥2 in 4%. Conclusion: In young active patients, the 10-year incidence of clinical radiographic PTOA after ACLR was 37% as defined by osteophytes and 23% as defined by joint space narrowing. The mean difference in the degree of osteophyte formation (≤1 grade in 85%) and joint space narrowing (≤1 grade in 96%) between the ACL-reconstructed and contralateral knees was small. Registration: NCT02717559 (ClinicalTrials.gov identifier) |
| تدمد: | 1552-3365 0363-5465 |
| DOI: | 10.1177/0363546521995182 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e613f9e2197c0485175d28f91921a8b https://doi.org/10.1177/0363546521995182 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....9e613f9e2197c0485175d28f91921a8b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15523365 03635465 |
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| DOI: | 10.1177/0363546521995182 |