Roles of the reproductive tract in modifications of the sperm membrane surface
| العنوان: | Roles of the reproductive tract in modifications of the sperm membrane surface |
|---|---|
| المؤلفون: | Kuo, Yu-Wen, Li, Sheng-Hsiang, Maeda, Kei-Ichiro, Gadella, Bart, Tsai, Pei-Shiue J, Sub Biologie van de mannelijke gameet, Sub Reproductie mannelijk, dES/dFAH FR |
| المساهمون: | Sub Biologie van de mannelijke gameet, Sub Reproductie mannelijk, dES/dFAH FR |
| المصدر: | The Journal of Reproduction and Development Journal of Reproduction and Development, 62(4), 337. Japanese Society of Animal Reproduction (JSAR) |
| بيانات النشر: | Japanese Society of Animal Reproduction, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Male, 0301 basic medicine, endocrine system, Somatic cell, Spermiogenesis, Review, Biology, Cell membrane, 03 medical and health sciences, 0302 clinical medicine, Human fertilization, medicine, Animals, Humans, reproductive and urinary physiology, Epididymis, Sperm-Ovum Interactions, 030219 obstetrics & reproductive medicine, urogenital system, Cell Membrane, Membrane modification, Oocyte, Spermatozoa, Sperm, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Fertilization, Immunology, Female, Animal Science and Zoology, Reproductive tract |
| الوصف: | Successful fertilization requires viable and functional spermatozoa to recognize and fuse with the oocyte. In most mammalian species, mature spermatozoa are not capable of fertilizing the oocytes immediately after ejaculation. However, unlike somatic cells, spermatozoa, after leaving the testis, are transcriptionally and translationally silent; therefore, upon completion of spermiogenesis, spermatozoa carry only a minimal amount of essential proteins on their membranes as well as within their restricted volume of cytoplasm. To develop into a fully functional and competent sperm that is capable of successful fertilization, modifications of the sperm membrane surface during its transit in the reproductive tracts is critical. These post-spermatogenesis modifications advance the maturation of epididymal spermatozoa. In addition, components secreted into the lumen of the reproductive tracts that are later added onto the sperm membrane surface also regulate (inhibit or activate) the functions of the spermatozoa. This acquisition of additional proteins from the reproductive tracts may compensate for the inactivity of morphologically mature spermatozoa. In this review, we discuss the contributions of the male and female genital tracts to modifications of the sperm membrane surface at different stages of fertilization. |
| وصف الملف: | image/pdf |
| تدمد: | 1348-4400 0916-8818 |
| DOI: | 10.1262/jrd.2016-028 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c62b836bca1275a77a1fa5c8dc3295e https://doi.org/10.1262/jrd.2016-028 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....9c62b836bca1275a77a1fa5c8dc3295e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13484400 09168818 |
|---|---|
| DOI: | 10.1262/jrd.2016-028 |