The correlation of non-motor symptoms and sleep on balance in Parkinson’s disease patients with normal cognition and mild cognitive impairment
| العنوان: | The correlation of non-motor symptoms and sleep on balance in Parkinson’s disease patients with normal cognition and mild cognitive impairment |
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| المؤلفون: | Nesrin Helvaci Yilmaz, Mevhibe Saricaoglu, Fahriye Feriha Özer, Lutfu Hanoglu |
| المصدر: | Irish Journal of Medical Science (1971 -). 190:1577-1584 |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Balance, Mild Cognitive Impairment, medicine.medical_specialty, Parkinson's disease, Disease, 030204 cardiovascular system & hematology, Parkinson’s Disease, 03 medical and health sciences, Cognition, 0302 clinical medicine, Physical medicine and rehabilitation, Quality of life, Rating scale, Humans, Medicine, Cognitive Dysfunction, 030212 general & internal medicine, Balance (ability), business.industry, Tinetti test, Non-Motor Symptoms, Parkinson Disease, General Medicine, medicine.disease, Berg Balance Scale, Quality of Life, Sleep, business |
| الوصف: | Background Parkinson's disease (PD) is characterized by non-motor symptoms (NMS) as well as by motor symptoms. Together with the impairment of cognitive functions, NMS and sleep also affect motor symptoms negatively. The aim of our study is to examine the correlation of NMS and sleep on balance in PD patients with normal cognition (PD-NC) and with mild cognitive impairment (PD-MCI). Methods A total of 69 patients were included in our study. Using the Standardized Mini-Mental State Examination, participants were divided into 2 groups, PD-NC and PD-MCI. Patients were assessed with the Unified Parkinson's Disease Rating Scale (UPDRS), the Berg Balance Scale (BBS), the Tinetti Balance Assessment Tool (TBAT), the Non-Motor Symptoms Questionnaire (NMSQ), and the Parkinson's Disease Questionnaire (PDQ-39). Results PD-MCI patients had statistically significant worse motor symptoms and more balance disorder compared to PD-NC (UPDRS: p = 0.009; BBS: p = 0.010; TBAT: p = 0.004). PD-MCI patients had greater severity of non-motor symptoms and worse sleep quality than the PD-NC group (NMSQ-total: p = 0.02; NMSQ-sleep total: p = 0.01). The evaluation has shown that with a diagnosis of MCI, NMS, and sleeping problems were correlated, and the correlation was associated with impairment of the balance function. While being more pronounced in the PD-MCI group, quality of life was affected in both groups (p < 0.05). Conclusion Our data demonstrate a negative effect on the balance function in patients with cognitive impairment suffering increased NMS and sleeping disorders. Treatment of these patients needs to concentrate on NMS and cognitive functions as much as on motor symptoms. |
| وصف الملف: | application/pdf |
| تدمد: | 1863-4362 0021-1265 |
| DOI: | 10.1007/s11845-020-02462-6 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9769351adae2ac09ddcec7fc454ec9dc https://doi.org/10.1007/s11845-020-02462-6 |
| Rights: | EMBARGO |
| رقم الانضمام: | edsair.doi.dedup.....9769351adae2ac09ddcec7fc454ec9dc |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18634362 00211265 |
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| DOI: | 10.1007/s11845-020-02462-6 |