Mycoplasmosis in Ferrets

التفاصيل البيبلوغرافية
العنوان: Mycoplasmosis in Ferrets
المؤلفون: Steven R. Bolin, Michael M. Garner, Ailam Lim, James H. Resau, Danielle R Desjardins, Cathy A. Johnson-Delaney, Carole A. Bolin, Matti Kiupel
المصدر: Emerging Infectious Diseases, Vol 18, Iss 11, Pp 1763-1770 (2012)
Emerging Infectious Diseases
بيانات النشر: Centers for Disease Control and Prevention, 2012.
سنة النشر: 2012
مصطلحات موضوعية: Microbiology (medical), disease outbreak, Canada, Epidemiology, lcsh:Medicine, Biology, medicine.disease_cause, Disease Outbreaks, respiratory tract disease, lcsh:Infectious and parasitic diseases, Mycoplasma, RNA, Ribosomal, 16S, medicine, Mustelidae, Animals, Mycoplasma Infections, lcsh:RC109-216, bacteria, Lung, ferret, Phylogeny, medicine.diagnostic_test, Research, Respiratory disease, lcsh:R, Ferrets, Outbreak, virus diseases, mycoplasmosis, Hyperplasia, respiratory system, medicine.disease, Virology, United States, Staining, Infectious Diseases, Bronchoalveolar lavage, Lymphatic system, medicine.anatomical_structure, Genes, Bacterial, Female
الوصف: A newly recognized respiratory disease of domestic ferrets is associated with a novel Mycoplasma species.
We report an outbreak of severe respiratory disease associated with a novel Mycoplasma species in ferrets. During 2009–2012, a respiratory disease characterized by nonproductive coughing affected ≈8,000 ferrets, 6–8 weeks of age, which had been imported from a breeding facility in Canada. Almost 95% became ill, but almost none died. Treatments temporarily decreased all clinical signs except cough. Postmortem examinations of euthanized ferrets revealed bronchointerstitial pneumonia with prominent hyperplasia of bronchiole-associated lymphoid tissue. Immunohistochemical analysis with polyclonal antibody against Mycoplasma bovis demonstrated intense staining along the bronchiolar brush border. Bronchoalveolar lavage samples from 12 affected ferrets yielded fast-growing, glucose-fermenting mycoplasmas. Nucleic acid sequence analysis of PCR-derived amplicons from portions of the 16S rDNA and RNA polymerase B genes failed to identify the mycoplasmas but showed that they were most similar to M. molare and M. lagogenitalium. These findings indicate a causal association between the novel Mycoplasma species and the newly recognized pulmonary disease.
اللغة: English
تدمد: 1080-6059
1080-6040
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::955bc479ed77af739316916e292a4a69
https://wwwnc.cdc.gov/eid/article/18/11/12-0072_article
Rights: OPEN
رقم الانضمام: edsair.doi.dedup.....955bc479ed77af739316916e292a4a69
قاعدة البيانات: OpenAIRE