Mycoplasmosis in Ferrets
العنوان: | Mycoplasmosis in Ferrets |
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المؤلفون: | Steven R. Bolin, Michael M. Garner, Ailam Lim, James H. Resau, Danielle R Desjardins, Cathy A. Johnson-Delaney, Carole A. Bolin, Matti Kiupel |
المصدر: | Emerging Infectious Diseases, Vol 18, Iss 11, Pp 1763-1770 (2012) Emerging Infectious Diseases |
بيانات النشر: | Centers for Disease Control and Prevention, 2012. |
سنة النشر: | 2012 |
مصطلحات موضوعية: | Microbiology (medical), disease outbreak, Canada, Epidemiology, lcsh:Medicine, Biology, medicine.disease_cause, Disease Outbreaks, respiratory tract disease, lcsh:Infectious and parasitic diseases, Mycoplasma, RNA, Ribosomal, 16S, medicine, Mustelidae, Animals, Mycoplasma Infections, lcsh:RC109-216, bacteria, Lung, ferret, Phylogeny, medicine.diagnostic_test, Research, Respiratory disease, lcsh:R, Ferrets, Outbreak, virus diseases, mycoplasmosis, Hyperplasia, respiratory system, medicine.disease, Virology, United States, Staining, Infectious Diseases, Bronchoalveolar lavage, Lymphatic system, medicine.anatomical_structure, Genes, Bacterial, Female |
الوصف: | A newly recognized respiratory disease of domestic ferrets is associated with a novel Mycoplasma species. We report an outbreak of severe respiratory disease associated with a novel Mycoplasma species in ferrets. During 2009–2012, a respiratory disease characterized by nonproductive coughing affected ≈8,000 ferrets, 6–8 weeks of age, which had been imported from a breeding facility in Canada. Almost 95% became ill, but almost none died. Treatments temporarily decreased all clinical signs except cough. Postmortem examinations of euthanized ferrets revealed bronchointerstitial pneumonia with prominent hyperplasia of bronchiole-associated lymphoid tissue. Immunohistochemical analysis with polyclonal antibody against Mycoplasma bovis demonstrated intense staining along the bronchiolar brush border. Bronchoalveolar lavage samples from 12 affected ferrets yielded fast-growing, glucose-fermenting mycoplasmas. Nucleic acid sequence analysis of PCR-derived amplicons from portions of the 16S rDNA and RNA polymerase B genes failed to identify the mycoplasmas but showed that they were most similar to M. molare and M. lagogenitalium. These findings indicate a causal association between the novel Mycoplasma species and the newly recognized pulmonary disease. |
اللغة: | English |
تدمد: | 1080-6059 1080-6040 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::955bc479ed77af739316916e292a4a69 https://wwwnc.cdc.gov/eid/article/18/11/12-0072_article |
Rights: | OPEN |
رقم الانضمام: | edsair.doi.dedup.....955bc479ed77af739316916e292a4a69 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 10806059 10806040 |
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