Terpenoids, essential oil composition, fatty acid profile, and biological activities of Anatolian Salvia fruticosa Mill
| العنوان: | Terpenoids, essential oil composition, fatty acid profile, and biological activities of Anatolian Salvia fruticosa Mill |
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| المؤلفون: | Ayşe Aslı Barla Demirkoz, Ufuk Kolak, Tuğba Kuşman, Gulacti Topcu, Mehmet Öztürk, Ayhan Ulubelen |
| المساهمون: | MÜ, KUŞMAN, TUBA |
| المصدر: | Volume: 37, Issue: 4 619-632 Turkish Journal of Chemistry |
| بيانات النشر: | TÜBİTAK, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Mühendislik, Anticholinesterase, law.invention, chemistry.chemical_compound, Salvia fruticosa, Engineering, Ursolic acid, law, Palmitoleic acid, Organic chemistry, Lamiaceae,Salvia fruticosa,secondary metabolites,abietane diterpenoids,triterpenoids,essential oil,fatty oil,antioxidant,anticholinesterase, Secondary Metabolites, Abietane Diterpenoids, Oleanolic acid, Essential oil, Fatty Oil, Chromatography, Lamiaceae, biology, Carnosic acid, General Chemistry, Triterpenoids, biology.organism_classification, Essential Oil, Oleic acid, chemistry, Stearic acid, Salvia Fruticosa, Antioxidant |
| الوصف: | Topcu, Gulacti/0000-0002-7946-6545; Ozturk, Mehmet/0000-0001-8932-4535; Topcu, Gulacti/0000-0002-7946-6545 WOS: 000321817800011 The hexane and dichloromethane extracts, obtained by re-extraction of the methanol extract of Salvia fruticosa Mill., afforded 7 diterpenoids (carnosol, carnosic acid, carnosic acid 12-methyl ether, rosmadial, isorosmanol, ferruginol, and manool), 4 triterpenoids (alpha-amyryltetracosanoate, oleanolic acid, ursolic acid, and erythrodiol), a steroid (3-acetylsitosterol), and a flavone (salvigenin). The galls (apples) of the collected plant were separately extracted with hexane to afford fatty acids composed mainly of oleic acid (29%), palmitoleic acid (29%), and stearic acid (23.20%), which exhibited high anticholinesterase activity, particularly against BChE. The essential oil, obtained from the aerial parts of the plant, exhibited high AChE inhibitory activity, consisting of mainly 1,8-cineol (58.89%). The antioxidant activity according to 6 complementary tests and anticholinesterase potential of the methanol extracts and triterpenoids alpha-amyryltetracosanoate, oleanolic acid, ursolic acid, and sitosterol acetate were also investigated, and methanol extract exhibited the highest antioxidant and anticholinesterase activity, surpassing the other tested extracts and pure compounds. Scientific and Technological Research Council of TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [TUBITAK - TBAG - 107T592] This work was supported by the Scientific and Technological Research Council of Turkey (TUBITAK - TBAG - 107T592). |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1300-0527 1303-6130 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9274dc13d31a430e882b45658821a196 https://dergipark.org.tr/tr/pub/tbtkchem/issue/11879/141980 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....9274dc13d31a430e882b45658821a196 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13000527 13036130 |
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