The Ophthalmic Performance of Hydrogel Contact Lenses Loaded with Silicone Nanoparticles
| العنوان: | The Ophthalmic Performance of Hydrogel Contact Lenses Loaded with Silicone Nanoparticles |
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| المؤلفون: | Ming-Chien Yang, Nguyen-Phuong-Dung Tran |
| المصدر: | Polymers, Vol 12, Iss 1128, p 1128 (2020) Polymers Volume 12 Issue 5 |
| بيانات النشر: | MDPI AG, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Materials science, Polymers and Plastics, Scanning electron microscope, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Article, Contact angle, lcsh:QD241-441, Oxygen permeability, chemistry.chemical_compound, Silicone, Dynamic light scattering, lcsh:Organic chemistry, PDMS, silicone nanoparticles, hydrogels, Polydimethylsiloxane, TEOS, General Chemistry, soft contact lenses, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Tetraethyl orthosilicate, Chemical engineering, chemistry, Self-healing hydrogels, 0210 nano-technology |
| الوصف: | In this study, silicone nanoparticles (SiNPs) were prepared from polydimethylsiloxane (PDMS) and tetraethyl orthosilicate (TEOS) via the sol-gel process. The resultant SiNPs were characterized by dynamic light scattering (DLS), transmission electron microscope (TEM), and scanning electron microscope (SEM). These SiNPs were then blended with 2-hydroxyethylmethacrylate (HEMA) and 1-vinyl-2-pyrrolidinone (NVP) before polymerizing into hydrogel contact lenses. All hydrogels were subject to characterization, including equilibrium water content (EWC), contact angle, and oxygen permeability (Dk). The average diameter of SiNPs was 330 nm. The results indicated that, with the increase of SiNPs content, the oxygen permeability increased, while the EWC was affected insignificantly. The maximum oxygen permeability attained was 71 barrer for HEMA-NVP lens containing 1.2 wt% of SiNPs with an EWC of 73%. These results demonstrate that by loading a small amount of SiNPs, the Dk of conventional hydrogel lenses can be improved greatly. This approach would be a new method to produce oxygen-permeable contact lenses. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2073-4360 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9202d74541e2f295581f9716c0126abc https://www.mdpi.com/2073-4360/12/5/1128 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....9202d74541e2f295581f9716c0126abc |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20734360 |
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