Conformal Fabrication of an Electrospun Nanofiber Mat on a 3d Ear Cartilage-shaped Hydrogel Collector Based on Hydrogel-Assisted Electrospinning
| العنوان: | Conformal Fabrication of an Electrospun Nanofiber Mat on a 3d Ear Cartilage-shaped Hydrogel Collector Based on Hydrogel-Assisted Electrospinning |
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| المؤلفون: | Jeong Myeong Lee, Hyun Il Ryu, Changryul Claud Yi, Jin Yeong Song, Seong Hwan Bae, Sang Min Park, Jae Woo Lee |
| المصدر: | Nanoscale Research Letters, Vol 16, Iss 1, Pp 1-11 (2021) Nanoscale Research Letters |
| بيانات النشر: | Research Square Platform LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Fabrication, Materials science, Nanochemistry, 3D printing, Conformal map, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Ear Cartilage, Tissue engineering, General Materials Science, Composite material, Materials of engineering and construction. Mechanics of materials, Nano Express, Electrospinning, business.industry, Ear cartilage, Nanofiber, 021001 nanoscience & nanotechnology, Condensed Matter Physics, 0104 chemical sciences, Hydrogel, TA401-492, 0210 nano-technology, business |
| الوصف: | Electrospinning is a common and versatile process to produce nanofibers and deposit them on a collector as a two-dimensional nanofiber mat or a three-dimensional (3D) macroscopic arrangement. However, 3D electroconductive collectors with complex geometries, including protruded, curved, and recessed regions, generally caused hampering of a conformal deposition and incomplete covering of electrospun nanofibers. In this study, we suggested a conformal fabrication of an electrospun nanofiber mat on a 3D ear cartilage-shaped hydrogel collector based on hydrogel-assisted electrospinning. To relieve the influence of the complex geometries, we flattened the protruded parts of the 3D ear cartilage-shaped hydrogel collector by exploiting the flexibility of the hydrogel. We found that the suggested fabrication technique could significantly decrease an unevenly focused electric field, caused by the complex geometries of the 3D collector, by alleviating the standard deviation by more than 70% through numerical simulation. Furthermore, it was experimentally confirmed that an electrospun nanofiber mat conformally covered the flattened hydrogel collector with a uniform thickness, which was not achieved with the original hydrogel collector. Given that this study established the conformal electrospinning technique on 3D electroconductive collectors, it will contribute to various studies related to electrospinning, including tissue engineering, drug/cell delivery, environmental filter, and clothing. Supplementary Information The online version contains supplementary material available at 10.1186/s11671-021-03571-6. |
| DOI: | 10.21203/rs.3.rs-291417/v1 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc3d790ff7702e74bce0723187b7018 https://doi.org/10.21203/rs.3.rs-291417/v1 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....8fc3d790ff7702e74bce0723187b7018 |
| قاعدة البيانات: | OpenAIRE |
| DOI: | 10.21203/rs.3.rs-291417/v1 |
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