Audiovisual Distraction Increases Prefrontal Cortical Neuronal Activity and Impairs Attentional Performance in the Rat
| العنوان: | Audiovisual Distraction Increases Prefrontal Cortical Neuronal Activity and Impairs Attentional Performance in the Rat |
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| المؤلفون: | Douglas G. Ririe, Thomas J. Martin, Benjamin S Schmidt, Salem J Martin, M. Danilo Boada, Susy A. Kim |
| المصدر: | Journal of Experimental Neuroscience Journal of Experimental Neuroscience, Vol 11 (2017) |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | 0301 basic medicine, Serial reaction time, 5 choice, neuron spike, brain, Local field potential, Bioinformatics, Behavioral or, behavioral disciplines and activities, lcsh:RC321-571, 03 medical and health sciences, 0302 clinical medicine, Distraction, Medicine, Premovement neuronal activity, Attention, prefrontal, Prefrontal cortex, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, action potentials, Original Research, local field potential, business.industry, General Neuroscience, musculoskeletal, neural, and ocular physiology, whole animal, electrophysiology, Cortex (botany), Electrophysiology, 030104 developmental biology, cortex, nervous system, business, Neuroscience, 030217 neurology & neurosurgery, psychological phenomena and processes, distraction |
| الوصف: | Involvement of attentional processes is generally evidenced by disruption of behavior in the presence of distracting stimuli. The medial prefrontal cortex (mPFC) seems to play a role in fine-tuning activity during attentional tasks. A novel titration variant of the 5-choice serial reaction time task (5-choice serial reaction time titration variant [5CTV]) that adjusts task difficulty based on subject performance was used to evaluate the effects of audiovisual distraction (DSTR) on performance and mPFC single spike activity and local field potential (LFP). Attention was impaired in the 5CTV from DSTR, and mPFC spike activity was increased, whereas LFP was reduced. The increased spike activity in the mPFC in conjunction with DSTR suggests that conflicting attentional demands may contribute to the reduced task performance. As both hypo- and hyperactivation of the mPFC may contribute to attentional disruption, further studies using the 5CTV are needed to understand mPFC activity changes in real time during disruption of performance by other types of behavioral or neurobiological manipulations. |
| تدمد: | 1179-0695 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ecaa9ad6082cea9f3591b36f00ba81d https://pubmed.ncbi.nlm.nih.gov/28469479 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....8ecaa9ad6082cea9f3591b36f00ba81d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 11790695 |
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