A ‘Sleeping Trojan Horse’ which transports metal ions into cells, localises in nucleoli, and has potential for bimodal fluorescence/PET imaging
| العنوان: | A ‘Sleeping Trojan Horse’ which transports metal ions into cells, localises in nucleoli, and has potential for bimodal fluorescence/PET imaging |
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| المؤلفون: | Joanne Cable, Coralie Ode Millet, Michael P. Coogan, Jonathan B. Court, Vanesa Fernández-Moreira, Anthony Joseph Hayes, David Lloyd, Catrin Ffion Williams, Flora L. Thorp-Greenwood |
| المصدر: | Chemical Communications. 47:3096 |
| بيانات النشر: | Royal Society of Chemistry (RSC), 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Silver, Nucleolus, Metal ions in aqueous solution, chemistry.chemical_element, Nanotechnology, Catalysis, Coordination Complexes, Cell Line, Tumor, Organometallic Compounds, Materials Chemistry, Humans, Fluorescent Dyes, Ions, Chemistry, Metals and Alloys, Cationic polymerization, Biological Transport, General Chemistry, Pet imaging, Rhenium, Fluorescence, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Membrane, Metals, Positron-Emission Tomography, Ceramics and Composites, Biophysics, Luminescence, Cell Nucleolus, Copper |
| الوصف: | A rhenium polypyridine-based molecular vessel is membrane impermeant when empty, but, upon loading with metal ions, the cationic form is taken up by MCF-7 cells, localising in nucleoli. The luminescence of the vessel and its copper binding ability suggest potential as a bimodal fluorescence/PET imaging agent. |
| تدمد: | 1364-548X 1359-7345 |
| DOI: | 10.1039/c1cc10141b |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d21b0731bb775d4d02ac2153dd16d00 https://doi.org/10.1039/c1cc10141b |
| رقم الانضمام: | edsair.doi.dedup.....8d21b0731bb775d4d02ac2153dd16d00 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1364548X 13597345 |
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| DOI: | 10.1039/c1cc10141b |