Factors determining the amount of residual urine in men with bladder outlet obstruction: Could it be a predictor for bladder contractility?

التفاصيل البيبلوغرافية
العنوان: Factors determining the amount of residual urine in men with bladder outlet obstruction: Could it be a predictor for bladder contractility?
المؤلفون: Amr G. Ali, Ahmed Abulfotooh, Ahmed Moussa, Mostafa Elmissiry, Gaber Ali
المصدر: Arab Journal of Urology
بيانات النشر: Elsevier, 2014.
سنة النشر: 2014
مصطلحات موضوعية: Urethral resistance, medicine.medical_specialty, ROC, receiver operating characteristic (curve), Urology, PdetQmax, detrusor pressure at Qmax, PFS, pressure-flow study, Qmax, maximum urinary flow rate, urologic and male genital diseases, Contractility, PVR, postvoid residual urine volume, Bladder outlet obstruction, Obstruction, Medicine, AUR, acute urinary retention, Residual urine, business.industry, BCI, bladder contractility index, Voiding dysfunction/Female urology Original article, Residual urine volume, female genital diseases and pregnancy complications, eye diseases, Urodynamics, Bladder contractility, URF, urethral resistance factor, sense organs, business
الوصف: Objective To determine from urodynamic data what causes an increased postvoid residual urine volume (PVR) in men with bladder outlet obstruction (BOO), urethral resistance or bladder failure, and to determine how to predict bladder contractility from the PVR. Patients and methods We analysed retrospectively the pressure-flow studies (PFS) of 90 men with BOO. Nine patients could not void and the remaining 81 were divided into three groups, i.e. A (30 men, PVR 450 mL). The division was made according to a receiver operating characteristic curve, showing that using a threshold PVR of 450 mL had the best sensitivity and specificity for detecting the start of bladder failure. Results The filling phase showed an increase in bladder capacity with the increase in PVR and a significantly lower incidence of detrusor overactivity in group C. The voiding phase showed a significant decrease in voided volume and maximum urinary flow rate (Qmax) as the PVR increased, while the urethral resistance factor (URF) increased from group A to B to C. The detrusor pressure at Qmax (PdetQmax) and opening pressure were significantly higher in group B, which had the highest bladder contractility index (BCI) and longest duration of contraction. Group C had the lowest BCI and the lowest PdetQmax. Conclusions In men with BOO, PVR results from increasing outlet resistance at the start and up to a PVR of 450 mL, where the bladder reaches its maximum compensation. At volumes of >450 mL, both the outlet resistance and bladder failure are working together, leading to detrusor decompensation.
اللغة: English
تدمد: 2090-5998
2090-598X
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d1d56ebf6b96802eb6c6a9d8a7813a2
http://europepmc.org/articles/PMC4435510
Rights: OPEN
رقم الانضمام: edsair.doi.dedup.....8d1d56ebf6b96802eb6c6a9d8a7813a2
قاعدة البيانات: OpenAIRE