Outcomes of lensectomy and risk factors for failure in spherophakic eyes with secondary glaucoma
| العنوان: | Outcomes of lensectomy and risk factors for failure in spherophakic eyes with secondary glaucoma |
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| المؤلفون: | Ramesh Kekunnaya, Sirisha Senthil, Subhadra Jalali, Praveen J John, Divya P Rao, Mohammed Hasnat Ali, Chandra S. Garudadri |
| المصدر: | British Journal of Ophthalmology. 102:790-795 |
| بيانات النشر: | BMJ, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Male, 0301 basic medicine, Intraocular pressure, medicine.medical_specialty, Visual acuity, Adolescent, genetic structures, medicine.medical_treatment, Visual Acuity, Glaucoma, Ophthalmologic Surgical Procedures, Cup-to-disc ratio, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Risk Factors, Ophthalmology, Lens, Crystalline, Glaucoma surgery, medicine, Humans, Child, Intraocular Pressure, Retrospective Studies, business.industry, Secondary glaucoma, Lens Subluxation, medicine.disease, eye diseases, Sensory Systems, 030104 developmental biology, medicine.anatomical_structure, 030221 ophthalmology & optometry, Female, sense organs, medicine.symptom, Complication, business, Optic disc |
| الوصف: | PurposeTo report the outcomes of lensectomy in spherophakic eyes with subluxated or dislocated crystalline lenses and secondary glaucoma.MethodsLensectomy was performed in 52 eyes, 36 eyes with lens subluxation and 16 eyes with lens dislocation with secondary glaucoma from 1991 to 2016. Glaucoma was diagnosed based on intraocular pressure (IOP) ≥22 mm Hg and/or glaucomatous optic disc damage. Complete success was defined as IOP ≥5 and ≤21 mm Hg without antiglaucoma medications (AGMs) or surgery, and eyes needing oral AGM or surgical intervention for IOP control or those with complication causing loss of light perception were considered failure.ResultsMedian (IQR) age at lensectomy was 12 (6–18) years, and median spherical equivalent was −14.5D (−23.7to −13). Median follow-up was 30.6 (5.4–103.4) months. Median logMAR (logarithm of minimal angle of resolution) visual acuity improved from 0.95 (0.6–1.8) to 0.4 (0.2–1.3) after lensectomy (p=0.01). Median IOP decreased from 22 mm Hg (17–31) to 14 mm Hg (11–19) at final follow-up (p=0.01). Median number of AGM decreased from 2 (2–3) to 1 (0–2) at final follow-up (p32 mm Hg) and larger cup to disc ratio at presentation were found to be significant risk factors for failure.ConclusionLensectomy was effective in controlling IOP in close to half of all eyes with spherophakia and secondary glaucoma, 40% eyes needed AGM and only 7.7% eyes needed glaucoma surgery for IOP control. In this cohort, younger age, higher IOP and larger cup to disc ratio at presentation were risk factors for poor glaucoma control after lensectomy. |
| تدمد: | 1468-2079 0007-1161 |
| DOI: | 10.1136/bjophthalmol-2017-310861 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf3f9d5c6b8bdfe1095e11e8b03ad3f https://doi.org/10.1136/bjophthalmol-2017-310861 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....8cf3f9d5c6b8bdfe1095e11e8b03ad3f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14682079 00071161 |
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| DOI: | 10.1136/bjophthalmol-2017-310861 |