Organocatalytic dynamic kinetic resolution of azlactones to construct chiral N-acyl amino acid oxime esters
| العنوان: | Organocatalytic dynamic kinetic resolution of azlactones to construct chiral N-acyl amino acid oxime esters |
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| المؤلفون: | Xiaohua Liu, Lili Lin, Xiaoming Feng, Xiaobin Lin, Kunru Yu |
| المصدر: | Chemical Communications. 51:14897-14900 |
| بيانات النشر: | Royal Society of Chemistry (RSC), 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | inorganic chemicals, Salt (chemistry), Stereoisomerism, Catalysis, Kinetic resolution, Lactones, chemistry.chemical_compound, Oximes, polycyclic compounds, Materials Chemistry, Organic chemistry, heterocyclic compounds, Amino Acids, chemistry.chemical_classification, Dipeptide, Chemistry, organic chemicals, Metals and Alloys, Esters, General Chemistry, Oxime, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Amino acid, Kinetics, Ceramics and Composites, Enantiomer |
| الوصف: | A direct strategy to obtain N-acyl amino acid oxime esters has been developed through the dynamic kinetic resolution of azlactones with oximes. In the presence of a chiral bisguanidinium salt catalyst, a variety of chiral N-acyl amino acid oxime esters were generated in excellent enantiomeric excesses (up to 97%) and high yields (up to 99%). The active oxime esters could be used in dipeptide synthesis. |
| تدمد: | 1364-548X 1359-7345 |
| DOI: | 10.1039/c5cc05534b |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba7151182b6bfc911f90ddd2a08de84 https://doi.org/10.1039/c5cc05534b |
| رقم الانضمام: | edsair.doi.dedup.....8ba7151182b6bfc911f90ddd2a08de84 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1364548X 13597345 |
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| DOI: | 10.1039/c5cc05534b |