A novel efficient dynamic programming algorithm for haplotype block partitioning

التفاصيل البيبلوغرافية
العنوان: A novel efficient dynamic programming algorithm for haplotype block partitioning
المؤلفون: Javad Zahiri, Ghasem Mahdevar, H. Ahrabian, Mehdi Sadeghi, Abbas Nowzari-Dalini
المصدر: Journal of Theoretical Biology. 267:164-170
بيانات النشر: Elsevier BV, 2010.
سنة النشر: 2010
مصطلحات موضوعية: Statistics and Probability, Haplotype block, Mathematical optimization, Optimization problem, Black People, Polymorphism, Single Nucleotide, White People, General Biochemistry, Genetics and Molecular Biology, Asian People, Humans, Alleles, Block (data storage), Mathematics, Biological data, General Immunology and Microbiology, Efficient algorithm, Applied Mathematics, Haplotype, General Medicine, Tag SNP, Dynamic programming, ComputingMethodologies_PATTERNRECOGNITION, Haplotypes, Modeling and Simulation, General Agricultural and Biological Sciences, Algorithm, Algorithms, Software
الوصف: In this paper, a new efficient algorithm is presented for haplotype block partitioning based on haplotype diversity. In this algorithm, finding the largest meaningful block that satisfies the diversity condition is the main goal as an optimization problem. The algorithm can be performed in polynomial time complexity with regard to the number of haplotypes and SNPs. We apply our algorithm on three biological data sets from chromosome 21 in three different population data sets from HapMap data bulk; the obtained results show the efficiency and better performance of our algorithm in comparison with three other well known methods.
تدمد: 0022-5193
DOI: 10.1016/j.jtbi.2010.08.019
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5df909b5ff35da62298d352b136f75
https://doi.org/10.1016/j.jtbi.2010.08.019
Rights: CLOSED
رقم الانضمام: edsair.doi.dedup.....8a5df909b5ff35da62298d352b136f75
قاعدة البيانات: OpenAIRE
الوصف
تدمد:00225193
DOI:10.1016/j.jtbi.2010.08.019