Disorders of the Vitreous and Vitreoretinal Interface
| العنوان: | Disorders of the Vitreous and Vitreoretinal Interface |
|---|---|
| المؤلفون: | Thomas A. Weingeist, David M. Brown |
| المصدر: | Pediatric Ophthalmology and Strabismus ISBN: 9781489905116 Handbook of Pediatric Retinal Disease ISBN: 9780387279329 |
| بيانات النشر: | Springer New York, 2003. |
| سنة النشر: | 2003 |
| مصطلحات موضوعية: | Scaffold, genetic structures, Retinal detachment, Solid material, medicine.disease, Posterior vitreous detachment, eye diseases, Extracellular matrix, chemistry.chemical_compound, chemistry, Hyaluronic acid, medicine, Biophysics, Bound water, sense organs, Collagen scaffold |
| الوصف: | The human vitreous is a complex extracellular matrix composed of 98% water and 2% solid material. The basic structure of the vitreous matrix is a scaffold of cross-linked collagen fibrils with hyaluronic acid molecules within the scaffold. Hyaluronic acid is very hydrophilic, and water molecules are attracted to the scaffold providing turgor and rigidity to the matrix. The vitreous is primarily a solid gel in children’s eyes but becomes progressively more liquid with aging. Liquefaction of the vitreous occurs when the hyaluronic acid depolymerizes, freeing the bound water and allowing the collagen scaffold to collapse. The collagen filaments then coalesce to form collagen fibers, causing the “floaters“ seen by patients with aging of the vitreous. |
| ردمك: | 978-1-4899-0511-6 978-0-387-27932-9 |
| DOI: | 10.1007/978-0-387-21753-6_32 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a34b6ce79e8474a224b065e1d8c4fce https://doi.org/10.1007/978-0-387-21753-6_32 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....8a34b6ce79e8474a224b065e1d8c4fce |
| قاعدة البيانات: | OpenAIRE |
| ردمك: | 9781489905116 9780387279329 |
|---|---|
| DOI: | 10.1007/978-0-387-21753-6_32 |