Serological markers and risk factors associated with Hepatitis B virus infection among Federal Capital Territory prison inmates, Nigeria: Should we be concerned?
| العنوان: | Serological markers and risk factors associated with Hepatitis B virus infection among Federal Capital Territory prison inmates, Nigeria: Should we be concerned? |
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| المؤلفون: | Ikeola A. Adeoye, Martins Onuoha, Kehinde Aderemi, Suleiman Idris, Patrick Nguku, Saheed Gidado, Damaris Amarachukwu Osunkwo, Chioma Dan-Nwafor, Elizabeth Adedire, Ekpedeme Udom, Adebobola Bashorun, Muhammad Shakir Balogun, Ibrahim Ade-Yusuf |
| المصدر: | PLoS ONE, Vol 16, Iss 3, p e0248045 (2021) PLoS ONE |
| بيانات النشر: | Public Library of Science (PLoS), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, HBsAg, Epidemiology, Social Sciences, medicine.disease_cause, Serology, Geographical Locations, 0302 clinical medicine, Risk Factors, Seroepidemiologic Studies, Medicine, Public and Occupational Health, 030212 general & internal medicine, Pathology and laboratory medicine, education.field_of_study, Multidisciplinary, Alcohol Consumption, Transmission (medicine), virus diseases, Infectious Disease Immunology, Middle Aged, Medical microbiology, Hepatitis B, Vaccination and Immunization, Vaccination, HBeAg, Viruses, Pathogens, Research Article, Adult, Hepatitis B virus, Science, 030231 tropical medicine, Population, Immunology, Nigeria, Microbiology, 03 medical and health sciences, Young Adult, Seroprevalence, Humans, education, Nutrition, Medicine and health sciences, Hepatitis B Surface Antigens, Marital Status, Biology and life sciences, business.industry, Prisoners, Viral pathogens, Organisms, Hepatitis viruses, digestive system diseases, Microbial pathogens, Diet, Cross-Sectional Studies, Prisons, Medical Risk Factors, People and Places, Africa, Law and Legal Sciences, Clinical Immunology, Preventive Medicine, Clinical Medicine, business, Criminal Justice System, Demography |
| الوصف: | Introduction Hepatitis B virus (HBV) infection is hyper-endemic in Nigeria. Prisons are high-risk environments for the spread of infectious diseases. Worldwide, seroprevalence of HBV infection is substantially higher among individuals in correctional facilities when compared to general population. We determined the seroprevalence and risk factors associated with HBV infection among Kuje prison inmates, Nigeria. Material and methods We conducted a prison facility based cross-sectional study. Interviewer administered questionnaires were used to obtain information on participants socio-demographic characteristics, HBV risk factors, previous HBV test and vaccination history. Blood samples collected from participants were analysed for HBsAg, HBsAb, HBcAb, HBeAg and HBeAb markers using rapid lateral chromatographic immunoassay kit. Univariate, bivariate, and multivariate analysis were performed. Results A total of 271 inmates (63 convicts and 208 awaiting trial inmates) were recruited into the study as participants. The mean age of the participants was 32.7 SD±9 years. HBV seroprevalence (HBsAg) of 13.7% (95% CI: 9.8–18.3) was found. 55.4% (95% CI: 49.2–61.4) of inmates were susceptible to HBV infection, 20.7% (95%CI; 16.0–26.0) had past HBV infection while 10.3% (95% CI: 7.0–14.6) had acquired natural or artificial HBV immunity. Factors found to be associated with current HBV infection (HBsAg) include age-group ≤25years (aOR = 8.0,95% CI: 2.9–22.3), being ever married (aOR = 4.2, 95% CI: 1.7–10.4) and history of alcohol consumption (aOR = 3.4, 95% CI: 1.3–8.4). Conclusion This study reveals a high seroprevalence of HBV infection among Kuje Prison inmates, hence the need to introduce prison-focused health intervention initiatives such as HBV screening, vaccination and care to reduce the transmission of HBV infection among inmates and ultimately the general population. |
| اللغة: | English |
| تدمد: | 1932-6203 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897acc4ed1490f4b077214c294155ea3 https://doaj.org/article/1a9864d0df264d209593604ea1ae24f4 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....897acc4ed1490f4b077214c294155ea3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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