Controversies in Reduction Mammoplasty: Being A 'Clean' Operation, Does It Mandate Antibiotic Prophylaxis?
العنوان: | Controversies in Reduction Mammoplasty: Being A 'Clean' Operation, Does It Mandate Antibiotic Prophylaxis? |
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المؤلفون: | Luiz Felipe Duarte Fernandes Vieira, Alberto Ferraz De Melo Neto, Álvaro Antônio Bandeira Ferraz, Marina Roggia Schio, Jonathan Augusto Vidal De Oliveira, Carlos Lacerda Andrade Almeida |
المصدر: | Surgical Infections. 17:596-600 |
بيانات النشر: | Mary Ann Liebert Inc, 2016. |
سنة النشر: | 2016 |
مصطلحات موضوعية: | Adult, Microbiology (medical), medicine.medical_specialty, Adolescent, Mammaplasty, Breast surgery, medicine.medical_treatment, Cefazolin, 030230 surgery, Reduction Mammoplasty, law.invention, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, medicine, Humans, Surgical Wound Infection, In patient, Antibiotic prophylaxis, Aged, Aged, 80 and over, business.industry, Incidence (epidemiology), Antibiotic Prophylaxis, Middle Aged, Anti-Bacterial Agents, Surgery, Infectious Diseases, 030220 oncology & carcinogenesis, Female, business, medicine.drug |
الوصف: | Considered a clean operation, breast surgery has surgical site infection (SSI) rates ranging from 4% to 18%, higher than the reference value for clean surgery (3.4%). The aim of this study was to measure the incidence of SSI in patients undergoing reduction mammoplasty with and without antibiotic prophylaxis, comparing the results and defining the value of antibiotic prophylaxis.The study was randomized, double-blinded, and interventional. Two groups were formed randomly, with 75 patients in each. Group 1 received prophylactic antibiotic (cefazolin 2 g 30 min before surgery with repetition at 1 g every 3 h during surgery), and Group 2 (control) did not have antibiotic prophylaxis. Patients were followed until the 30th post-operative day for identification of SSI.There were 13 cases of SSI, 3 in Group 1 (4.1%) and 10 in Group 2 (13.9%) (p = 0.039). Their secretion cultures were positive for Staphylococcus aureus. There were more cases of SSI in patients having greater resections (n = 9), but the difference was not significant (p = 0.051).Infection was significantly more common in the group that did not receive prophylaxis. |
تدمد: | 1557-8674 1096-2964 |
DOI: | 10.1089/sur.2016.072 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::886a66ff55d6e9f0b83e3d93a5e61345 https://doi.org/10.1089/sur.2016.072 |
Rights: | CLOSED |
رقم الانضمام: | edsair.doi.dedup.....886a66ff55d6e9f0b83e3d93a5e61345 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 15578674 10962964 |
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DOI: | 10.1089/sur.2016.072 |