Non-Hunner’s Interstitial Cystitis Is Different from Hunner’s Interstitial Cystitis and May Be Curable by Uterosacral Ligament Repair

التفاصيل البيبلوغرافية
العنوان: Non-Hunner’s Interstitial Cystitis Is Different from Hunner’s Interstitial Cystitis and May Be Curable by Uterosacral Ligament Repair
المؤلفون: Klaus Goeschen, Darren M. Gold, Bernhard Liedl, Alexander Yassouridis, Peter Petros
المصدر: Urologia Internationalis. 106:649-657
بيانات النشر: S. Karger AG, 2022.
سنة النشر: 2022
مصطلحات موضوعية: Ligaments, Urology, Cystitis, Interstitial, Humans, Female, Nocturia, Chronic Pain, Pelvic Pain, Retrospective Studies
الوصف: Background: The posterior fornix syndrome (PFS) was first described in 1993 as a predictably occurring group of symptoms: chronic pelvic pain (CPP), urge, frequency, nocturia, emptying difficulties/urinary retention, caused by uterosacral ligament (USL) laxity, and cured by repair thereof. Summary: Our hypothesis was that non-Hunner’s interstitial cystitis (IC) and PFS are substantially equivalent conditions. The primary objective was to determine if there was a causal relationship between IC and pelvic organ prolapse (POP). The secondary objective was to assess whether other pelvic symptoms were present in patients with POP-related IC and if so, which ones? How often did they occur? A retrospective study was performed in 198 women who presented with CPP, uterine/apical prolapse (varying degrees), and PFS symptoms, all of whom had been treated by posterior USL sling repair. We compared their PFS symptoms with known definitions of IC, CPP, and bladder symptoms. To check our hypothesis for truth or falsity, we used a validated questionnaire, “simulated operations” (mechanically supporting USLs with a vaginal speculum test to test for reduction of urge and pain), transperineal ultrasound and urodynamics. Key Messages: 198 patients had CPP and 313 had urinary symptoms which conformed to the definition for non-Hunner’s IC. The cure rate after USL sling repair was CPP 74%, urge incontinence 80%, frequency 79.6%, abnormal emptying 53%, nocturia 79%, obstructive defecation 80%. Our findings seem to support our hypothesis that non-Hunner’s IC and PFS may be similar conditions; also, non-Hunner IC/BPS may be a separate or lesser disease entity from “Hunner lesion disease”. More rigorous scientific investigation, preferably by RCT, will be required.
تدمد: 1423-0399
0042-1138
DOI: 10.1159/000524321
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879d8be706629aba15d1a53ab716825a
https://doi.org/10.1159/000524321
Rights: OPEN
رقم الانضمام: edsair.doi.dedup.....879d8be706629aba15d1a53ab716825a
قاعدة البيانات: OpenAIRE
الوصف
تدمد:14230399
00421138
DOI:10.1159/000524321