Three-Dimensional Bacterial Behavior near Dynamic Surfaces Formed by Degradable Polymers
| العنوان: | Three-Dimensional Bacterial Behavior near Dynamic Surfaces Formed by Degradable Polymers |
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| المؤلفون: | Qilei Song, Guangzhao Zhang, Xiangjun Gong, Junpeng Zhao, Chunfeng Ma, Meng Qi |
| المصدر: | Langmuir. 33:13098-13104 |
| بيانات النشر: | American Chemical Society (ACS), 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Materials science, Polymers, Surface Properties, Polyesters, Nanotechnology, 02 engineering and technology, Microscopy, Atomic Force, 010402 general chemistry, medicine.disease_cause, 01 natural sciences, Bacterial Adhesion, Microscopy, Escherichia coli, Electrochemistry, medicine, General Materials Science, Spectroscopy, chemistry.chemical_classification, biology, Lipase, Surfaces and Interfaces, Polymer, Adhesion, 021001 nanoscience & nanotechnology, Condensed Matter Physics, biology.organism_classification, 0104 chemical sciences, Polyester, chemistry, Chemical engineering, Degradation (geology), Digital holographic microscopy, 0210 nano-technology, Bacteria |
| الوصف: | Understanding the behavior of bacteria near biodegradable surfaces is critical for the development of biomedical and antibiofouling materials. By using digital holographic microscopy (DHM), we investigated the three-dimensional (3D) behavior of Escherichia coli and Pseudomonas sp. in lipase-containing aquatic environments near dynamic surfaces constructed by biodegradable poly(ε-caprolactone) (PCL)-based polymers in real time. As the enzymatic degradation rate increases, the percentage of near-surface subdiffusive bacteria and consequently, the irreversible adhesion decreases. Atomic force microscopy (AFM) measurements reveal that the adhesion force between bacteria and the surfaces decreases with an increasing degradation rate. In addition, the degradation products elicit a negative chemotactic response in E. coli, further driving them away from the dynamic surfaces through more frequent tumbling motion. Our study clearly demonstrates that bacterial adhesion can be reduced on dynamic surfaces formed by degradable polymers. |
| تدمد: | 1520-5827 0743-7463 |
| DOI: | 10.1021/acs.langmuir.7b02806 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873c292fed2c670711196a99a5e483bb https://doi.org/10.1021/acs.langmuir.7b02806 |
| رقم الانضمام: | edsair.doi.dedup.....873c292fed2c670711196a99a5e483bb |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15205827 07437463 |
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| DOI: | 10.1021/acs.langmuir.7b02806 |