A low-cost tebuconazole-based screening test for azole-resistant aspergillus fumigatus

التفاصيل البيبلوغرافية
العنوان: A low-cost tebuconazole-based screening test for azole-resistant aspergillus fumigatus
المؤلفون: Amelie P Brackin, Thomas R. Sewell, Alireza Abdolrasouli, Matthew C. Fisher, Jennifer M. G. Shelton
المساهمون: Natural Environment Research Council (NERC), Medical Research Council (MRC)
بيانات النشر: Wiley-Blackwell, 2020.
سنة النشر: 2020
مصطلحات موضوعية: Antifungal, Azoles, Screening test, Genotype, medicine.drug_class, tebuconazole, Azole resistance, Microbial Sensitivity Tests, Microbiology, Aspergillus fumigatus, 03 medical and health sciences, chemistry.chemical_compound, azole resistance, Drug Resistance, Fungal, Virology, medicine, 030304 developmental biology, Tebuconazole, chemistry.chemical_classification, 0303 health sciences, biology, 030306 microbiology, business.industry, Environmental surveillance, General Medicine, Triazoles, biology.organism_classification, Biotechnology, Fungicides, Industrial, chemistry, Azole, Parasitology, business, fungal diagnostic, antifungal
الوصف: The global emergence of azole resistance in Aspergillus fumigatus is resulting in health and food security concerns. Rapid diagnostics and environmental surveillance methods are key to understanding the distribution and prevalence of azole resistance. However, such methods are often associated with high costs and are not always applicable to laboratories based in the least-developed countries. Here, we present and validate a low-cost screening protocol that can be used to differentiate between azole-susceptible "wild-type" and azole-resistant A. fumigatus isolates. © 2020 The Authors. Basic Protocol 1: Preparation of Tebucheck multi-well plates Basic Protocol 2: Inoculation of Tebucheck multi-well plates.
اللغة: English
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872d1da9e867e9dc4d91fd1726e8b268
http://hdl.handle.net/10044/1/82714
Rights: OPEN
رقم الانضمام: edsair.doi.dedup.....872d1da9e867e9dc4d91fd1726e8b268
قاعدة البيانات: OpenAIRE