Clinical Radiographic Predictors of Response to Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea
| العنوان: | Clinical Radiographic Predictors of Response to Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea |
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| المؤلفون: | Brendan T. Keenan, Xin Wu, Clara H Lee, James W Reese, Raj C. Dedhia, Everett G Seay, Richard Schwab |
| المصدر: | Otolaryngol Head Neck Surg |
| بيانات النشر: | Wiley, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Male, Hypoglossal Nerve, Cephalometry, Radiography, Electric Stimulation Therapy, Stimulation, Article, 03 medical and health sciences, 0302 clinical medicine, Predictive Value of Tests, medicine, Humans, Prospective Studies, Prospective cohort study, Aged, Retrospective Studies, Sleep Apnea, Obstructive, Soft palate, business.industry, Organ Size, Middle Aged, medicine.disease, Obstructive sleep apnea, Treatment Outcome, medicine.anatomical_structure, 030228 respiratory system, Otorhinolaryngology, Anesthesia, Female, Surgery, Palate, Soft, business, Hypoglossal nerve, 030217 neurology & neurosurgery |
| الوصف: | OBJECTIVE. To determine if clinically acquired cephalometric measurements, specifically soft palate size, can predict hypoglossal nerve stimulation outcomes. STUDY DESIGN. Combined prospective cohort study and retrospective review. SETTING. US sleep otolaryngology training program. METHODS. Adults with obstructive sleep apnea and apneahypopnea index greater than 15 events/h who underwent hypoglossal nerve stimulation. Eligible subjects had diagnostic preoperative sleep studies and full-night efficacy postoperative studies for analysis. Lateral neck x-rays were obtained as part of routine clinical care and measured for key cephalometric variables by trained head and neck radiologists. Continuous variables were compared using the Student t test, while χ(2) testing was used for categorical variables. RESULTS. Fifty-one patients met all study criteria. On average, patients were white, middle aged, and overweight. Following hypoglossal nerve stimulation, the overall cohort achieved a significant apnea-hypopnea index reduction from 36.7 events/h to 20.6 events/h (P < .01) and a response rate of 47% (defined as apnea-hypopnea index reduction >50% and apnea-hypopnea index |
| تدمد: | 1097-6817 0194-5998 |
| DOI: | 10.1177/0194599820963141 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c9c8393ab262574d880bff6671e200 https://doi.org/10.1177/0194599820963141 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....85c9c8393ab262574d880bff6671e200 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10976817 01945998 |
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| DOI: | 10.1177/0194599820963141 |