Distribution of genetically characterized yeasts and its antifungals susceptibility in the hospital environment
| العنوان: | Distribution of genetically characterized yeasts and its antifungals susceptibility in the hospital environment |
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| المؤلفون: | Pedro Rassier dos Santos, Evandro Pereira, Carolina Lambrecht Gonçalves, Patrícia da Silva Nascente, C. H. Freitas, Marcos Roberto Alves Ferreira, Fabricio Rochedo Conceição |
| المصدر: | Anais da Academia Brasileira de Ciências, Vol 93, Iss suppl 3 (2021) Anais da Academia Brasileira de Ciências, Volume: 93 Supplement 3, Article number: e20201070, Published: 12 NOV 2021 Anais da Academia Brasileira de Ciências v.93 suppl.3 2021 Anais da Academia Brasileira de Ciências Academia Brasileira de Ciências (ABC) instacron:ABC |
| بيانات النشر: | Academia Brasileira de Ciências, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Candida spp, Antifungal Agents, Multidisciplinary, Science, Fungal genetics, Microbial Sensitivity Tests, Drug resistance, Biology, Candida parapsilosis, biology.organism_classification, Hospitals, Microbiology, Candida tropicalis, Drug Resistance, Fungal, medicine, Humans, Terbinafine, Fluconazole, Candida, medicine.drug, Pichia |
| الوصف: | Candida spp. is one of the main pathogens associated with nosocomial infection in Brazil and worldwide. The aim of this study was to evaluate the distribution of Candida yeasts in the ICU and their susceptibility to the antifungal agents terbinafine and fluconazole. The samples were collected by swabbing nine surfaces in the ICU of a hospital located in Pelotas, RS. These isolates were genetically characterized by sequencing the internal transcript spacer (ITS) using the primers ITS1 and ITS4. The test against antifungals was performed by Microdilution in Broth (CLSI-M27-A4). 64 yeasts identified as Candida parapsilosis (45.31%; n = 29), Meyerozyma (Pichia) guilliermondii (28.12%; n = 18), Claviceps lusitaneae (25%; n = 16) and Candida tropicalis (1, 56%; n = 1) mostly at the counter used for handling medicines and food distribution (68.75%; n = 44). Susceptibility to antifungals varied between species. These results describe potentially pathogenic Candida species as contaminants in the ICU environment. The study environment is a potential source of exogenous infection for hospitalized patients. |
| وصف الملف: | text/html |
| اللغة: | English |
| تدمد: | 1678-2690 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a1c582f5013d0547b15211041a77f2 http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652021000600917&tlng=en |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....85a1c582f5013d0547b15211041a77f2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16782690 |
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