Randomized Double-Blinded Comparative Study of Intravenous Nalbuphine and Tramadol for the Treatment of Postspinal Anesthesia Shivering
| العنوان: | Randomized Double-Blinded Comparative Study of Intravenous Nalbuphine and Tramadol for the Treatment of Postspinal Anesthesia Shivering |
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| المؤلفون: | Shio Priye, Barun Ram, Deepak Kumar Nirala, Vishwanath Kumar, Jay Prakash, Pradip Kumar Bhattacharya |
| المصدر: | Anesthesia, Essays and Researches |
| بيانات النشر: | Wolters Kluwer - Medknow, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | tramadol, animal structures, business.industry, Nausea, Sedation, Neuraxial blockade, Nalbuphine, Context (language use), Anesthesia, postspinal anesthesia shivering, Materials Chemistry, medicine, Shivering, Vomiting, Original Article, Tramadol, medicine.symptom, business, medicine.drug |
| الوصف: | Context: Shivering is one of the most commonly recognized complications of the central neuraxial blockade. For optimal perioperative care, control of postspinal anesthesia shivering is essential. Aims: The present study designed to compare the clinical efficacy, hemodynamic parameters, and side effects of nalbuphine and tramadol for control of postspinal anesthesia shivering. Settings and Design: This was a prospective, randomized, double-blind study. Materials and Methods: This study was conducted on 90 American Society of Anesthesiologists Physical Status I and II patients of either gender, aged between 18 and 60 years, who subsequently developed shivering grade 3 or 4, scheduled for different surgical procedures under spinal anesthesia. The patients were randomized into two groups of 45 patients each to receive either nalbuphine 0.06 mg.kg−1 (Group N) or tramadol 1 mg.kg−1 (Group T). Grade of shivering, onset of shivering, time interval for cessation of shivering, response rate at 5 and 30 min, rescue dose, hemodynamic parameters, and side effects were observed at scheduled intervals. Statistical Analysis Used: Independent t-test and Chi-square/Fisher's exact test were used to analyze the data. Results: The time taken for cessation of shivering was significantly less with nalbuphine in comparison with tramadol (P < 0.05). It was observed that the response time at 5 and 30 min and rescue dose requirement for control of shivering were not much difference (P > 0.05). Conclusions: Both nalbuphine and tramadol are effective; however, the time taken for cessation of shivering is significantly less with nalbuphine when compared to tramadol. Furthermore, tramadol causes significantly more nausea and vomiting; however, nalbuphine causes significantly more sedation. |
| اللغة: | English |
| تدمد: | 2229-7685 0259-1162 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b02f99a6d12c240b52d3d806b9bece http://europepmc.org/articles/PMC8159045 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....83b02f99a6d12c240b52d3d806b9bece |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22297685 02591162 |
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