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Acute myeloid leukemia with mutated nucleophosmin 1: an immunogenic acute myeloid leukemia subtype and potential candidate for immune checkpoint inhibition

التفاصيل البيبلوغرافية
العنوان: Acute myeloid leukemia with mutated nucleophosmin 1: an immunogenic acute myeloid leukemia subtype and potential candidate for immune checkpoint inhibition
المؤلفون: Susanne Hofmann, Michael Schmitt, Hubert Schrezenmeier, Hartmut Döhner, Jochen Greiner, M Wiesneth, Lars Bullinger, Marlies Götz, Donald Bunjes
المصدر: Haematologica. 102(12)
سنة النشر: 2017
مصطلحات موضوعية: 0301 basic medicine, Adult, Male, congenital, hereditary, and neonatal diseases and abnormalities, NPM1, medicine.medical_treatment, Potential candidate, 03 medical and health sciences, 0302 clinical medicine, hemic and lymphatic diseases, medicine, Humans, Online Only Articles, neoplasms, Aged, Nucleophosmin, business.industry, Immunity, Cancer, Myeloid leukemia, Nuclear Proteins, Hematology, Immunotherapy, Middle Aged, medicine.disease, Virology, Immune checkpoint, Leukemia, Leukemia, Myeloid, Acute, 030104 developmental biology, 030220 oncology & carcinogenesis, Mutation, Cancer research, Female, business
الوصف: Clinical and preclinical data suggest that acute myeloid leukemia (AML) with mutated nucleophosmin 1 ( NPM1 mut) might constitute an immunogenic leukemia subtype. In general, AML with NPM1 mut correlates with better prognosis, but the underlying mechanisms still remain to be elucidated. Our group
تدمد: 1592-8721
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e9e2e8b430f4421bc7ec9771d382b6
https://pubmed.ncbi.nlm.nih.gov/28935849
Rights: OPEN
رقم الانضمام: edsair.doi.dedup.....82e9e2e8b430f4421bc7ec9771d382b6
قاعدة البيانات: OpenAIRE
الوصف
تدمد:15928721