Association of folic acid, vitamin B12, and intelligence scores in epileptic children
| العنوان: | Association of folic acid, vitamin B12, and intelligence scores in epileptic children |
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| المؤلفون: | Mones M. Abu Shady, Esam Galal, Mohamed EL-Sonbaty, Marwa M. El-Sonbaty, Mahmoud M. Masoud, Eman R. Youness, Ali Abd Elaziz, Walaa Alshasrany Abu Elhamd |
| المصدر: | Applied Neuropsychology: Child. 11:45-49 |
| بيانات النشر: | Informa UK Limited, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Pediatrics, medicine.medical_specialty, Serum folic acid, Intelligence, 03 medical and health sciences, Epilepsy, Folic Acid, 0302 clinical medicine, Developmental and Educational Psychology, medicine, Humans, 0501 psychology and cognitive sciences, Vitamin B12, Child, Cognitive impairment, Association (psychology), Valproic Acid, 05 social sciences, Childhood disease, medicine.disease, Vitamin B 12, Neuropsychology and Physiological Psychology, Folic acid, Psychology, 030217 neurology & neurosurgery, 050104 developmental & child psychology |
| الوصف: | Epilepsy is a serious childhood disease associated with cognitive impairment. Our aim was to investigate the possible association of serum folic acid, vitamin B12, and intelligence scores in epileptic children. A group of 30 children with established diagnosis of idiopathic epilepsy for at least one year as well as another group of 30 nonepileptic healthy children as the control group were recruited for analysis. Cognitive performance was assessed by a battery of psychological tests that covers verbal and nonverbal intelligence. Serum B12 level was significantly lower in patients than the control group (264.17 ± 58.07, 450.55 ± 134.9, respectively). No significant difference was detected between patients and the control group regarding serum folic acid level. Verbal, performance, and total IQ were significantly lower in patients than the control group (83.2 ± 3.08 vs. 95.8 ± 6.22, 78.4 ± 10.68 vs. 91.3 ± 2.45, and 180.6 ± 6.58 vs. 93.5 ± 3.02, respectively). However, no significant correlation was detected in folic acid, vitamin B 12, and cognitive scores. Epileptic children were five times more at risk of having low IQ (verbal, performance, and total)85 than the control group (OR = 4.754, 95% CI 13.047-1031.316 |
| تدمد: | 2162-2973 2162-2965 |
| DOI: | 10.1080/21622965.2020.1747020 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825c342a4b4d6b04253e973190a9c869 https://doi.org/10.1080/21622965.2020.1747020 |
| رقم الانضمام: | edsair.doi.dedup.....825c342a4b4d6b04253e973190a9c869 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 21622973 21622965 |
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| DOI: | 10.1080/21622965.2020.1747020 |