التفاصيل البيبلوغرافية
العنوان:
Gene–environment interactions between air pollution and biotransformation enzymes and risk of birth defects
المؤلفون:
Cecilia Lee , Amy Padula , Gary M. Shaw , S. Hammond , F. Lurmann , Wei Yang , Kathleen Schultz
المصدر:
Birth Defects Res
بيانات النشر:
Wiley, 2021.
سنة النشر:
2021
مصطلحات موضوعية:
0301 basic medicine , Embryology , Transposition of Great Vessels , Health, Toxicology and Mutagenesis , air pollution , Buccal swab , Air pollution , Physiology , cleft lip , 030105 genetics & heredity , medicine.disease_cause , Toxicology , Biotransformation , Pregnancy , 2.1 Biological and endogenous factors , 2.2 Factors relating to the physical environment , d-TGA , Aetiology , CYP2A6 , General Environmental Science , chemistry.chemical_classification , cleft palate , Pediatric , TGA , education.field_of_study , biology , Liver-Specific Organic Anion Transporter 1 , gastroschisis , heart defect , Environmental chemistry , Female , environment , orofacial defect , Population , gene– , Article , tetralogy of fallot , 03 medical and health sciences , gene-environment , Clinical Research , Air Pollution , Genetics , medicine , Humans , Climate-Related Exposures and Conditions , d‐ , gene , education , Gene , Pollutant , congenital anomalies , Gastroschisis , Prevention , Mouth Mucosa , medicine.disease , Teratology , Enzyme , 030104 developmental biology , chemistry , Case-Control Studies , Pediatrics, Perinatology and Child Health , biology.protein , General Earth and Planetary Sciences , Gene-Environment Interaction , SLCO1B1 , Developmental Biology
الوصف:
Genetic and environmental factors have been observed to influence risks for birth defects, though few studies have investigated gene-environment interactions. Our aim was to examine the interaction terms of gene variants in biotransformation enzyme pathways and air pollution exposures in relation to risk of several structural birth defects. We evaluated the role of ambient air pollutant exposure (nitrogen dioxide [NO2 ], nitrogen oxide, carbon monoxide, particulate matter
وصف الملف:
application/pdf
تدمد:
2472-1727
DOI:
10.1002/bdr2.1880
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd4fa5fe5b3ee38a7613cdd8d069053 https://doi.org/10.1002/bdr2.1880
Rights:
OPEN
رقم الانضمام:
edsair.doi.dedup.....7fd4fa5fe5b3ee38a7613cdd8d069053
قاعدة البيانات:
OpenAIRE