Vitamin D status and prevalent early age-related macular degeneration in African Americans and Caucasians: The Atherosclerosis Risk in Communities (ARIC) Study
| العنوان: | Vitamin D status and prevalent early age-related macular degeneration in African Americans and Caucasians: The Atherosclerosis Risk in Communities (ARIC) Study |
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| المؤلفون: | Jing Nie, Kristin J. Meyers, Chris Andrews, Pamela L. Lutsey, Amy E. Millen, Michael J. LaMonte, Barbara E.K. Klein, Ronald Klein, Julie A. Mares, Michelle W. Sahli |
| المصدر: | The journal of nutrition, health & aging. 21:772-780 |
| بيانات النشر: | Springer Science and Business Media LLC, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Nutritional Status, Medicine (miscellaneous), 030204 cardiovascular system & hematology, Article, White People, Macular Degeneration, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Internal medicine, Epidemiology, Prevalence, Vitamin D and neurology, Humans, Medicine, Prospective Studies, Vitamin D, Nutrition and Dietetics, business.industry, Odds ratio, Middle Aged, Macular degeneration, Atherosclerosis, medicine.disease, eye diseases, Confidence interval, Surgery, Black or African American, Cross-Sectional Studies, Logistic Models, Blood pressure, Cohort, 030221 ophthalmology & optometry, Female, sense organs, Geriatrics and Gerontology, business, Biomarkers, Cohort study |
| الوصف: | Vitamin D status has been hypothesized to protect against development of early age-related macular degeneration (AMD) via its anti-inflammatory properties and its possible beneficial influence on blood pressure control. We investigated the association between vitamin D status and prevalent early AMD in a community-based cohort. This was a cross-sectional study. This was a secondary data analysis of already existing data from the Atherosclerosis Risk in Communities Study (ARIC) cohort collected from 1990 to 1995. There were 9,734 (7,779 Caucasians, 1,955 African American) ARIC participants (aged 46 to 70 at visit 2 [1990-1992]) with 25(OH)D data available at visit 2, AMD assessment at visit 3 (1993-1995), and complete covariate data. Vitamin D status was assessed with serum 25-hydroxyvitamin D (25(OH)D) concentrations from bloods drawn at visit 2. Prevalent, early AMD (n=511) was assessed at visit 3 (1993-95) with nonmydriatic retinal photographs of one randomly chosen eye. Logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for early AMD by categories of 25(OH)D in nmol/L (deficient |
| تدمد: | 1760-4788 1279-7707 1990-1992 |
| DOI: | 10.1007/s12603-016-0827-6 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f864d3f7d2ba033dac9b49ddb8d6bbf https://doi.org/10.1007/s12603-016-0827-6 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....7f864d3f7d2ba033dac9b49ddb8d6bbf |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17604788 12797707 19901992 |
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| DOI: | 10.1007/s12603-016-0827-6 |