Extent of atherosclerosis after 11-year prospective follow-up in patients with early rheumatoid arthritis was affected by disease severity at diagnosis
العنوان: | Extent of atherosclerosis after 11-year prospective follow-up in patients with early rheumatoid arthritis was affected by disease severity at diagnosis |
---|---|
المؤلفون: | Anna Södergren, Ewa Berglin, I. Bjorsenius, Solbritt Rantapää-Dahlqvist |
المصدر: | Scandinavian Journal of Rheumatology. 49:443-451 |
بيانات النشر: | Informa UK Limited, 2020. |
سنة النشر: | 2020 |
مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Immunology, Blood Pressure, Disease, Severity of Illness Index, Arthritis, Rheumatoid, Rheumatology, Disease severity, Risk Factors, Internal medicine, Early ra, medicine, Humans, Immunology and Allergy, In patient, Prospective Studies, Prospective cohort study, Aged, Rheumatology and Autoimmunity, Reumatologi och inflammation, business.industry, Age Factors, General Medicine, Early rheumatoid arthritis, Middle Aged, Atherosclerosis, medicine.disease, Rheumatoid arthritis, Disease Progression, Female, business, Follow-Up Studies |
الوصف: | Objective: Cardiovascular disease (CVD) is increased among patients with rheumatoid arthritis (RA). The underlying cause is not clear. In this prospective study, patients with early RA were investigated for associations between subclinical atherosclerosis and CVD risk factors as well as inflammation. Method: At diagnosis, RA patients were recruited into a prospective study. A subgroup was included (n = 55) for ultrasound measurements of intima–media thickness (IMT) at inclusion (T0), and after 5 years (T5) and 11 years (T11). Thirty-one age and gender-matched controls were also included for comparison. Results: IMT increased significantly between T0 and T11 among patients and controls (p 0.05 for all). In simple regression models, IMT at T11 was significantly associated with age (p |
وصف الملف: | application/pdf |
تدمد: | 1502-7732 0300-9742 |
DOI: | 10.1080/03009742.2020.1767200 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f1e3a49397ae7d88f984df719460530 https://doi.org/10.1080/03009742.2020.1767200 |
Rights: | OPEN |
رقم الانضمام: | edsair.doi.dedup.....7f1e3a49397ae7d88f984df719460530 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 15027732 03009742 |
---|---|
DOI: | 10.1080/03009742.2020.1767200 |