A randomized clinical study using optical coherence tomography to evaluate the short-term effects of high-intensity interval training on cardiac allograft vasculopathy: a HITTS substudy
| العنوان: | A randomized clinical study using optical coherence tomography to evaluate the short-term effects of high-intensity interval training on cardiac allograft vasculopathy: a HITTS substudy |
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| المؤلفون: | Kari Nytrøen, Muzammil Rafique, Jouke Dijkstra, Lars Gullestad, Bjørn Bendz, Katrine Rolid, Ole Geir Solberg, Niels Ramsing Holm, Ketil Lunde, Omeed Neghabat |
| المصدر: | Clinical Transplantation, 36(1). WILEY Rafique, M, Solberg, O G, Gullestad, L, Bendz, B, Holm, N R, Neghabat, O, Dijkstra, J, Nytrøen, K, Rolid, K & Lunde, K 2022, ' A randomized clinical study using optical coherence tomography to evaluate the short-term effects of high-intensity interval training on cardiac allograft vasculopathy : a HITTS substudy ', Clinical Transplantation, vol. 36, no. 1, 14488 . https://doi.org/10.1111/ctr.14488 |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, medicine.medical_treatment, High-Intensity Interval Training, Cardiac allograft vasculopathy, Interval training, rehabilitation, Optical coherence tomography, Internal medicine, Clinical endpoint, medicine, Humans, vasculopathy, Heart transplantation, Transplantation, medicine.diagnostic_test, business.industry, clinical trial, Allografts, Intensity (physics), cardiovascular system, Cardiology, Heart Transplantation, Population study, sense organs, business, High-intensity interval training, Tomography, Optical Coherence |
| الوصف: | Cardiac allograft vasculopathy (CAV) remains a leading cause of long-term mortality after heart transplantation. Both preventive measures and treatment options are limited. This study aimed to evaluate the short-term effects of high-intensity interval training (HIT) on CAV in de novo heart transplant (HTx) recipients as assessed by optical coherence tomography (OCT). The study population was a subgroup of the 81-patient HITTS study in which HTx recipients were randomized to HIT or moderate intensity continuous training (MICT) for nine consecutive months. OCT images from baseline and 12 months were compared to assess CAV progression. The primary endpoint was defined as the change in the mean intima area. Paired OCT data were available for 56 patients (n = 23 in the HIT group and n = 33 in the MICT group). The intima area in the entire study population increased by 25% [from 1.8±1.4mm2 to 2.3±2.0mm2 , p |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 0902-0063 |
| DOI: | 10.1111/ctr.14488 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a5f7eff77b74642a5b59881a9846d8a http://hdl.handle.net/1887/3567527 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....7a5f7eff77b74642a5b59881a9846d8a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 09020063 |
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| DOI: | 10.1111/ctr.14488 |