A novel differential diagnostic model based on multiple biological parameters for immunoglobulin A nephropathy
| العنوان: | A novel differential diagnostic model based on multiple biological parameters for immunoglobulin A nephropathy |
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| المؤلفون: | Yong Wang, Zhennan Dong, Zhangming Yan, Yaping Tian, Xingwang Jia, Jing Gao |
| المصدر: | BMC Medical Informatics and Decision Making, Vol 12, Iss 1, p 58 (2012) BMC Medical Informatics and Decision Making |
| بيانات النشر: | BMC, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Immunoglobulin A, Adult, Male, medicine.medical_specialty, Biopsy, Health Informatics, Logistic regression, Fibrinogen, Kidney, urologic and male genital diseases, lcsh:Computer applications to medicine. Medical informatics, Gastroenterology, Models, Biological, Sensitivity and Specificity, Diagnosis, Differential, Young Adult, Internal medicine, medicine, Humans, Primary kidney disease, Retrospective Studies, Multiparameter analysis, biology, medicine.diagnostic_test, business.industry, Health Policy, Retrospective cohort study, Glomerulonephritis, Glomerulonephritis, IGA, IgA nephropathy, Middle Aged, medicine.disease, Linear discriminant analysis, Computer Science Applications, Immunology, biology.protein, lcsh:R858-859.7, Female, Differential diagnosis, business, Biomarkers, medicine.drug, Research Article |
| الوصف: | BackgroundImmunoglobulin A nephropathy (IgAN) is the most common form of glomerulonephritis in China. An accurate diagnosis of IgAN is dependent on renal biopsies, and there is lack of non-invasive and practical classification methods for discriminating IgAN from other primary kidney diseases. The objective of this study was to develop a classification model for the auxiliary diagnosis of IgAN using multiparameter analysis with various biological parameters.MethodsTo establish an optimal classification model, 121 cases (58 IgAN vs. 63 non-IgAN) were recruited and statistically analyzed. The model was then validated in another 180 cases.ResultsOf the 57 biological parameters, there were 16 parameters that were significantly different (P ConclusionsThese models possess potential clinical applications in distinguishing IgAN from other primary kidney diseases. |
| اللغة: | English |
| تدمد: | 1472-6947 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7808750ada151f7299a8dc0a9f7c8fa4 http://www.biomedcentral.com/1472-6947/12/58 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....7808750ada151f7299a8dc0a9f7c8fa4 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14726947 |
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