Immunologic Parameters in Cord Blood Indicating Early-Onset Sepsis
| العنوان: | Immunologic Parameters in Cord Blood Indicating Early-Onset Sepsis |
|---|---|
| المؤلفون: | H.-B. Von Stockhausen, Thomas Roos, J. Martius, Lothar Schrod, P. Rutsch, T. Lehrnbecher |
| المصدر: | Neonatology. 70:206-212 |
| بيانات النشر: | S. Karger AG, 1996. |
| سنة النشر: | 1996 |
| مصطلحات موضوعية: | Haemophilus Infections, Population, Physiology, Adhesion (medicine), Umbilical cord, Sepsis, medicine, Humans, education, Escherichia coli Infections, Fetus, education.field_of_study, Interleukin-6, business.industry, Cell adhesion molecule, Interleukin-8, Infant, Newborn, Interleukin, Fetal Blood, Intercellular Adhesion Molecule-1, medicine.disease, Haemophilus influenzae, medicine.anatomical_structure, Cord blood, Pediatrics, Perinatology and Child Health, Immunology, business, Developmental Biology |
| الوصف: | Different immunologic parameters were measured in cord blood to test their usefulness in the early diagnosis of early-onset sepsis. Cord blood levels of circulating intercellular adhesion molecule-1 (cICAM-1), interleukin-6 (IL-6) and interleukin-8 (IL-8) were significantly elevated in septic compared to nonseptic neonates. No significant difference between either population was seen for cord blood C3a and elastase-α1-proteinase inhibitor complex (Eα1PI). Measured concentrations of cICAM-1, IL-6 and IL-8 in fetal and maternal blood did not correlate, indicating that the neonate’s response to sepsis is clearly different from the mother. Our data suggest that cord blood measurements of cICAM-1, IL-6 and IL-8 might be useful in identifying neonates with early-onset sepsis. |
| تدمد: | 1661-7819 1661-7800 |
| DOI: | 10.1159/000244366 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e16e2a4214c54957476c4d2412fc48 https://doi.org/10.1159/000244366 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....77e16e2a4214c54957476c4d2412fc48 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16617819 16617800 |
|---|---|
| DOI: | 10.1159/000244366 |