Glycemic control and BMI changes after endoscopic implantation of a duodenojejunal bypass liner compared with laparoscopic Roux-en-Y gastric bypass surgery: a propensity score matching analysis
| العنوان: | Glycemic control and BMI changes after endoscopic implantation of a duodenojejunal bypass liner compared with laparoscopic Roux-en-Y gastric bypass surgery: a propensity score matching analysis |
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| المؤلفون: | Sarah J. Günthert, Aysegül Aksan, Oliver Schröder, Günther Meyer, Johannes Hausmann, Jürgen Stein, Christine Stier |
| المصدر: | Surgical Endoscopy. 36:5979-5985 |
| بيانات النشر: | Springer Science and Business Media LLC, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Adult, Glycated Hemoglobin, Male, Gastric Bypass, Glycemic Control, Middle Aged, Body Mass Index, Obesity, Morbid, Treatment Outcome, Diabetes Mellitus, Type 2, Weight Loss, Humans, Female, Laparoscopy, Surgery, Obesity, Propensity Score, Retrospective Studies |
| الوصف: | Both laparoscopic Roux-en-Y gastric bypass (RYGB) and duodenojejunal bypass liner (DJBL) have been shown to induce weight loss and dramatically ameliorate type 2 diabetes mellitus (T2DM). Since DJBL implantation causes nutrients to pass through the duodenum without contact with the digestive juices and the duodenal mucosa, its mechanisms have been suggested to mimic those of RYGB. This study aimed to compare the outcomes of these two bariatric procedures in terms of glycemic control and BMI in patients with obesity and T2DM.A retrospective observational cohort propensity score-weighted comparison of laparoscopic Roux-en-Y gastric bypass (RYGB) vs duodenojejunal bypass liner (DJBL) was conducted in patients with obesity and T2DM undergoing either procedure from 05/2014 to 12/2017. Propensity scores were weighted for body weight, body mass index (BMI), and glycated hemoglobin A1c (HbA1c). The primary outcome was comparative improvement of HbA1c. Secondary comparative effectiveness outcomes were decrease of body weight and BMI.Forty-six patients were included: 21 (10 male, 11 female; mean age 50.6 ± 11.7 years) underwent RYGB, while DJBL was implanted in 25 (10 male, 15 female; 52.5 ± 9.5 years). After twelve months, mean ΔBMI was 11.54 ± 4.47 kg/mRYGB and DJBL seem to be associated with similar remission rates of hyperglycemia after one year. However, RYGB induces more significant weight loss than DJBL. |
| تدمد: | 1432-2218 0930-2794 |
| DOI: | 10.1007/s00464-022-09177-y |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77ab54b652b0fb3792f0fcd80c53821f https://doi.org/10.1007/s00464-022-09177-y |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....77ab54b652b0fb3792f0fcd80c53821f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14322218 09302794 |
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| DOI: | 10.1007/s00464-022-09177-y |