Long-term outcomes of percutaneous or surgical treatment in left main disease
| العنوان: | Long-term outcomes of percutaneous or surgical treatment in left main disease |
|---|---|
| المؤلفون: | Juan G, Chiabrando, Giovanni M, Vescovo, Marco, Lombardi, Marco G, Del Buono, Francisco J, Romeo, Daniel H, Berrocal, Luis, Guzman, Giuseppe, Biondi-Zoccai, Antonio, Abbate |
| المصدر: | Minerva Cardiology and Angiology. 69 |
| بيانات النشر: | Edizioni Minerva Medica, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Percutaneous Coronary Intervention, Treatment Outcome, Humans, Drug-Eluting Stents, Coronary Artery Disease, Coronary Artery Bypass, Cardiology and Cardiovascular Medicine |
| الوصف: | Long-term efficacy and safety of either surgical or percutaneous treatment left main coronary artery disease treatment is lacking.We conducted a systematic review and meta-analysis of the most updated randomized clinical trials that compared the efficacy of coronary artery bypass surgery (CABG) or percutaneous coronary intervention (PCI) for the Left Main Coronary Artery (LMCA) disease. It was also conducted a systematic search of PubMed, Google Scholar, reference lists of relevant articles, and Medline. The search utilized the following terms: "left main PCI versus CABG," "drug-eluting stents," "bypass surgery" and "left main stenting." The search of articles compatible with our inclusion and exclusion criteria was performed from inception through April 2020 and returned a combined total of 304 articles.We identified 6 studies, providing data on 5812 patients. The mean follow-up was 6.7 years. PCI was associated with an increased risk of major vascular events (MACE) (IRR 1.24, 95% CI [1.03-1.67], P0.01), and coronary revascularization (IRR 1.69, 95% CI [1.42-2.03], P0.01) compared to CABG. Furthermore, all-cause death, MI and stroke events were not statistically different between the two therapeutic revascularization methodologies (IRR 1.06, 95% CI [0.90-1.24], P=0.47, IRR 1.35, 95% CI [0.84-2.16], P=0.03 and IRR 0.66, 95% CI [0.43-1.01], P=0.05, respectively).LMCA PCI has an overall same survival compared to CABG in the long term follow-up. Nevertheless, MACE and revascularization events were more frequent in PCI compared to CABG. |
| تدمد: | 2724-5772 2724-5683 |
| DOI: | 10.23736/s2724-5683.20.05370-0 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::743f92b73531119a7e8d342ef165de97 https://doi.org/10.23736/s2724-5683.20.05370-0 |
| رقم الانضمام: | edsair.doi.dedup.....743f92b73531119a7e8d342ef165de97 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 27245772 27245683 |
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| DOI: | 10.23736/s2724-5683.20.05370-0 |