Tumor Growth of Suspected Meningiomas in Clinically Healthy 80-year-olds: A Follow up Five Years Later
| العنوان: | Tumor Growth of Suspected Meningiomas in Clinically Healthy 80-year-olds: A Follow up Five Years Later |
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| المؤلفون: | Susanne Jungwirth, Peter Fischer, Wolfgang Krampla, W Pfisterer, K. H. Tragl, T Leitha, S Newrkla, W. Hruby |
| المصدر: | Zentralblatt für Neurochirurgie - Central European Neurosurgery. 69:182-186 |
| بيانات النشر: | Georg Thieme Verlag KG, 2008. |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | medicine.medical_specialty, Contrast Media, Gadolinium, Asymptomatic, Neurosurgical Procedures, Cohort Studies, Meningioma, medicine, Humans, Tumor growth, Insulin-Like Growth Factor I, Aged, 80 and over, Tumor size, medicine.diagnostic_test, business.industry, Incidence (epidemiology), Magnetic resonance imaging, medicine.disease, Magnetic Resonance Imaging, Surgery, Cohort, Disease Progression, Neurology (clinical), Radiology, medicine.symptom, business, Follow-Up Studies, Cohort study |
| الوصف: | Background The incidence of clinically silent meningiomas in 75-year-old individuals was determined five years ago in the Vienna Transdanube Ageing Study (VITA). At the time a watch-and-wait approach was recommended in cases of incidentally discovered meningiomas. Methods 420 out of the initial cohort of 532 test persons underwent control investigations after 2.5 and 5 years. Six of the nine known tumors were measured again and the patients underwent clinical, neurological and psychological tests. Changes in tumor size were determined and all new tumors seen on MRI investigation were carefully reviewed. Results Tumor growth was minimal in all six cases that were followed over the entire period. Two of the original meningioma patients had died and one patient had undergone tumor resection. Conclusions The watch-and-wait approach recommended after the VITA study was confirmed by the present investigation. Tumor growth was slow in all cases; no clinical symptoms have been registered thus far. The intervals between control investigations may even be prolonged depending on the location of the tumor. In this age group the operation appears to pose a greater risk than the presence of an asymptomatic tumor. |
| تدمد: | 1438-9746 0044-4251 |
| DOI: | 10.1055/s-2008-1080940 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715dbcae8c9f77b57f201f56414de6b0 https://doi.org/10.1055/s-2008-1080940 |
| رقم الانضمام: | edsair.doi.dedup.....715dbcae8c9f77b57f201f56414de6b0 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14389746 00444251 |
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| DOI: | 10.1055/s-2008-1080940 |