The Positive Impact of Resistance Training on Muscle Mass and Serum Leptin Levels in Patients 2–7 Years Post-Roux-en-Y Gastric Bypass: A Controlled Clinical Trial
| العنوان: | The Positive Impact of Resistance Training on Muscle Mass and Serum Leptin Levels in Patients 2–7 Years Post-Roux-en-Y Gastric Bypass: A Controlled Clinical Trial |
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| المؤلفون: | Nathalia Pizato, Kelly Grace Magalhães, Isabela Nogueira Martins Sena Rios, Fernando Lamarca, Kênia Mara Baiocchi de Carvalho, Flávio Teixeira Vieira, Heloisa Antoniella Braz de Melo |
| المصدر: | Obesity Surgery. 31:3758-3767 |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Leptin, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Gastric Bypass, Adipokine, 030209 endocrinology & metabolism, Inflammation, Gastroenterology, Body Mass Index, Proinflammatory cytokine, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Weight Loss, medicine, Humans, Nutrition and Dietetics, Adiponectin, business.industry, Muscles, Resistance training, Resistance Training, Roux-en-Y anastomosis, Obesity, Morbid, Clinical trial, 030211 gastroenterology & hepatology, Surgery, medicine.symptom, business, Body mass index |
| الوصف: | Resistance training program (RTP) assist the maintenance of optimal body composition and inflammatory response modulation in individuals in late Roux-en-Y gastric bypass (RYGB). This study aimed to investigate the effect of RTP on body composition and serum inflammatory profile in individuals 2–7 years post-RYGB. Volunteers were matched on body mass index (BMI), age, sex, and years after surgery, and they were allocated as control or RTP group. Body composition, visceral fat area (VFA), and inflammatory serum markers were measured at baseline and after 12 weeks of RTP. The sample baseline characteristics (n = 63; BMI = 29.7 ± 5.3 kg/m2) were similar between the groups. After intervention, the RTP group presented higher fat-free mass (Δ 1.17 ± 1.12 kg, p = 0.003) and skeletal muscle mass (Δ 0.77 ± 0.66 kg, p = 0.002) and decreased leptin levels (Δ –0.15 ± 0.60 pg/mL, p = 0.028). Ultrasensitive C-reactive protein (CRPus), interleukin-6, adiponectin, and monocyte chemotactic protein-1 showed no significant time-by-group interaction. After the categorization of RTP group individuals by VFA median values (129.8 cm2, IQR 90.9; 152.5), participants with VFA values above the median presented a significant decrease in CRPus (Δ –0.20 mg/L, IQR –7.59; –0.03, p = 0.022) when compared to the participants with VFA values below the median. The RTP improved individuals’ body composition by a modest but significant enhancing muscle mass and decreasing serum leptin and CRPus levels, especially in individuals with VFA values above the median. RTPs assist in maintaining the adequate body composition as they contribute to a decrease in proinflammatory markers in long-term RYGB. |
| تدمد: | 1708-0428 0960-8923 |
| DOI: | 10.1007/s11695-021-05494-8 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eef8b3667f8e585c4baaddfc8f66468 https://doi.org/10.1007/s11695-021-05494-8 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....6eef8b3667f8e585c4baaddfc8f66468 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17080428 09608923 |
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| DOI: | 10.1007/s11695-021-05494-8 |