Unusual morphologic features of low‐grade endometrial stromal sarcoma: A case report
| العنوان: | Unusual morphologic features of low‐grade endometrial stromal sarcoma: A case report |
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| المؤلفون: | Ling Li Meng, Xiu Peng Jia, Li Xia Lu, Hui Zhi Zhang, Xiao Han Shen, Zheng Hua Piao, Rong Ge, Wen Ying Yu |
| المصدر: | Journal of Clinical Laboratory Analysis. 36 |
| بيانات النشر: | Wiley, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Adult, Microbiology (medical), Sarcoma, Endometrial Stromal, Biochemistry (medical), Clinical Biochemistry, Public Health, Environmental and Occupational Health, Hematology, Prognosis, Endometrial Neoplasms, Medical Laboratory Technology, Endometrial Stromal Tumors, Humans, Immunology and Allergy, Female |
| الوصف: | Endometrial stromal tumours are uncommon tumours of the uterus. They mainly occur in perimenopausal women. Tumours with typical clinicopathological features do not usually pose diagnostic problems. However, rare clinicopathological features can occur, and clinicians without significant experience may have difficulty diagnosing these tumours and managing these patients.Herein, we report a case of endometrial stromal sarcoma that occurred in a 25-year-old woman. The pathological features, immunophenotype, treatment and prognosis were discussed.The tumour revealed morphological heterogeneity, and there were similar proliferative-type endometrial stromal cells, an extensive amount of mature adipose tissue, and prominent rhabdomyoblastic and smooth muscle cells. Histopathological and immunohistochemical studies confirmed low-grade endometrial stromal sarcoma with smooth muscle, adipocytic and rhabdomyoblastic differentiation (approximately 60% were differentiated tissues). The final treatment of the tumour was total abdominal hysterectomy with bilateral salpingo-oophorectomy. There was no evidence of recurrence for 109 months postoperatively.We found that low-grade endometrial stromal tumours with extensive adipocytic and prominent rhabdomyoblastic differentiation are misdiagnosed because they are infrequent. They must be differentiated from rhabdomyosarcoma with accurate identification of adipocytes, and long-term follow-up is needed. |
| تدمد: | 1098-2825 0887-8013 |
| DOI: | 10.1002/jcla.24502 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee30e6e0def8c0dd476adde5a02cc99 https://doi.org/10.1002/jcla.24502 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....6ee30e6e0def8c0dd476adde5a02cc99 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10982825 08878013 |
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| DOI: | 10.1002/jcla.24502 |