Probabilistic dietary exposure to phycotoxins in a recreational shellfish harvester subpopulation (France)
| العنوان: | Probabilistic dietary exposure to phycotoxins in a recreational shellfish harvester subpopulation (France) |
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| المؤلفون: | Gwendolina Limon, Cyndie Picot, Alain-Claude Roudot, Gaël Durand, Dominique Parent-Massin |
| المساهمون: | Laboratoire d'Evaluation du Risque Chimique pour le COnsommateur (LERCCO), Université de Brest (UBO), Institut Départemental d'analyse de conseil et d'expertise en Hygiène alimentaire, Eau et environnement et Santé Animale (IDHESA), IDHESA |
| المصدر: | Journal of Exposure Science and Environmental Epidemiology Journal of Exposure Science and Environmental Epidemiology, Nature Publishing Group, 2012, epub ahead of print. ⟨10.1038/jes.2012.44⟩ |
| بيانات النشر: | HAL CCSD, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Adult, Tolerable daily intake, Epidemiology, Population, 0211 other engineering and technologies, Food Contamination, 02 engineering and technology, 010501 environmental sciences, Biology, Toxicology, 01 natural sciences, Young Adult, chemistry.chemical_compound, Environmental health, Okadaic Acid, Humans, 14. Life underwater, education, Chronic toxicity, Shellfish, Aged, 0105 earth and related environmental sciences, Aged, 80 and over, 021110 strategic, defence & security studies, Reference dose, Phycotoxin, education.field_of_study, Kainic Acid, Models, Statistical, business.industry, Public Health, Environmental and Occupational Health, technology, industry, and agriculture, Domoic acid, food and beverages, Middle Aged, Food safety, Pollution, Diet, Fishery, chemistry, Phytoplankton, Marine Toxins, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, France, business |
| الوصف: | International audience; Phycotoxins, secondary phytoplankton metabolites, are considered as an important food safety issue because their accumulation by shellfish may render them unfit for human consumption. However, the likely intakes of phycotoxins via shellfish consumption are almost unknown because both contamination and consumption data are very scarce. Thus, two 1-year surveys were conducted (through the same population: recreational shellfish harvesters and from the same geographical area) to assess: shellfish consumption and contamination by major toxins (domoic acid (DA) group, okadaic acid (OA) group and spirolides (SPXs)). Recreational shellfish harvesters had been targeted as an at-risk subpopulation because they consume more shellfish than general population and because they eat not only commercial shellfish species controlled by official authorities but also their own harvests of shellfish species may be in non-controlled areas and more over shellfish species non-considered in the official control species. Then, these two kinds of data were combined with deterministic and probabilistic approaches for both acute and chronic exposures, on considering the impact of shellfish species and cooking on phycotoxin levels. For acute risk, monitoring programs seem to be adequate for DAs, whereas OAs could be a matter of concern for high consumers (their acute intakes were up to ninefold the acute reference dose (ARfD)). About chronic risk, OAs are a matter of concern. The daily OAs intakes were close to the ARfD, which is, by definition, greater than the tolerable daily intake. Moreover, SPX contamination is low but regular, no (sub)chronic SPX toxicity data exist; but in case of (sub)chronic toxicity, SPX exposure should be considered.Journal of Exposure Science and Environmental Epidemiology advance online publication, 4 July 2012; doi:10.1038/jes.2012.44. |
| اللغة: | English |
| تدمد: | 1559-0631 1559-064X |
| DOI: | 10.1038/jes.2012.44⟩ |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c217ebd0ac7e2e2c92d68d95e5306d2 https://hal.univ-brest.fr/hal-00764537 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....6c217ebd0ac7e2e2c92d68d95e5306d2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15590631 1559064X |
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| DOI: | 10.1038/jes.2012.44⟩ |