Dedifferentiated chondrosarcoma with muscle and cytokeratin differentiation in the anaplastic component
| العنوان: | Dedifferentiated chondrosarcoma with muscle and cytokeratin differentiation in the anaplastic component |
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| المؤلفون: | Peter A. Dervan, B. J. Hurson, J. O'loughlin |
| المصدر: | Histopathology. 12:517-526 |
| بيانات النشر: | Wiley, 1988. |
| سنة النشر: | 1988 |
| مصطلحات موضوعية: | Adult, musculoskeletal diseases, Pathology, medicine.medical_specialty, animal structures, Histology, Chondrosarcoma, Bone Neoplasms, Ribs, Biology, Pathology and Forensic Medicine, Cytokeratin, Keratin, medicine, Humans, Pelvic Bones, Rhabdomyosarcoma, Anaplasia, chemistry.chemical_classification, Muscles, General Medicine, Middle Aged, musculoskeletal system, medicine.disease, Immunohistochemistry, Cell Transformation, Neoplastic, chemistry, Keratins, Female, Desmin, Sarcoma, medicine.symptom |
| الوصف: | Dedifferentiated chondrosarcoma is a biphasic tumour, comprising well-differentiated chondrosarcoma and an anaplastic non-cartilaginous sarcoma juxtaposed but distinct from each other. Two cases of dedifferentiated chondrosarcoma, one primary and one recurrent, demonstrated muscle differentiation when studied with monoclonal antibodies to muscle specific actin, desmin and myoglobin. One of the tumours was also positive for cytokeratin, identified by AE1/AE3 and CAM 5.2 antibodies. Our findings are consistent with the concept that these tumours are capable of diverse patterns of morphological and immunophenotypic differentiation. |
| تدمد: | 1365-2559 0309-0167 |
| DOI: | 10.1111/j.1365-2559.1988.tb01971.x |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a70bf10a87cf9d16b98fe5012383aec https://doi.org/10.1111/j.1365-2559.1988.tb01971.x |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....6a70bf10a87cf9d16b98fe5012383aec |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13652559 03090167 |
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| DOI: | 10.1111/j.1365-2559.1988.tb01971.x |