Implementation of a Cellulitis Management Plan in Three Australian Regional Health Services to Address an Evidence–Practice Gap in Antibiotic Prescribing
| العنوان: | Implementation of a Cellulitis Management Plan in Three Australian Regional Health Services to Address an Evidence–Practice Gap in Antibiotic Prescribing |
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| المؤلفون: | James Farquharson, Kathrine Summerhayes, Jaclyn L. Bishop, N. Deborah Friedman, Raquel Cowan, Mark Jones, David C. M. Kong, Thomas R. Schulz, Kirsty Buising, Mary Smith, Roxanne Tucker |
| المصدر: | Antibiotics Antibiotics, Vol 10, Iss 1288, p 1288 (2021) Volume 10 Issue 11 |
| بيانات النشر: | MDPI AG, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Microbiology (medical), medicine.medical_specialty, medicine.drug_class, Antibiotics, RM1-950, appropriateness, Biochemistry, Microbiology, Article, Antibiotic prescribing, Health services, stewardship, Primary outcome, antibiotic, medicine, Pharmacology (medical), cellulitis, General Pharmacology, Toxicology and Pharmaceutics, business.industry, medicine.disease, Infectious Diseases, Cellulitis, Emergency medicine, Therapeutics. Pharmacology, rural, business |
| الوصف: | Despite the availability of evidence-based guidelines, antibiotics for cellulitis remain inappropriately prescribed. This evidence–practice gap is more evident in low-resource settings, such as rural hospitals. This implementation study developed and introduced a cellulitis management plan to improve antibiotic prescribing for cellulitis in three health services in regional Australia. Appropriateness of antibiotic prescribing for cellulitis at Day 1 was the primary outcome measure. Adults with ICD-10-AM codes for lower-limb cellulitis admitted as inpatients of the three health services between May and November 2019 (baseline, n = 165) and March and October 2020 (post-implementation, n = 127) were included in the assessment. The uptake of the cellulitis management plan was 29.1% (37/127). The appropriateness of antibiotic prescribing for cellulitis at Day 1 was similar at baseline (78.7%, 144/183) and in the intention-to-treat post-implementation group (81.8%, 126/154) [95% CI −5.6% to 11.3%, p = 0.50]. Commencement of the cellulitis management plan resulted in a non-statistically significant increase in antibiotic appropriateness at Day 1 compared to when a cellulitis management plan was not commenced (88.1% vs. 79.5% 95% CI −5.6% to 19.8% p = 0.20) Evaluation of more real-world strategies to address evidence–practice gaps, such as the appropriateness of antibiotic prescribing for cellulitis, is required. |
| وصف الملف: | application/pdf |
| تدمد: | 2079-6382 |
| DOI: | 10.3390/antibiotics10111288 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a25ae3e95075ffd0316a9b3af9a7455 https://doi.org/10.3390/antibiotics10111288 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....6a25ae3e95075ffd0316a9b3af9a7455 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20796382 |
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| DOI: | 10.3390/antibiotics10111288 |