Lossen rearrangement by Rh(iii )-catalyzed C–H activation/annulation of aryl hydroxamates with alkynes: access to quinolone-containing amino acid derivatives
| العنوان: | Lossen rearrangement by Rh( |
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| المؤلفون: | Dmitry A. Petropavlovskikh, Oleg A. Filippov, Sergey E. Nefedov, Daria V. Vorobyeva, Ivan A. Godovikov, Sergey N. Osipov |
| المصدر: | Organic & Biomolecular Chemistry. 19:9421-9426 |
| بيانات النشر: | Royal Society of Chemistry (RSC), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | chemistry.chemical_classification, Annulation, Chemistry, Aryl, Organic Chemistry, Triple bond, Biochemistry, Medicinal chemistry, Amino acid, Catalysis, chemistry.chemical_compound, Lossen rearrangement, Moiety, Organic synthesis, Physical and Theoretical Chemistry |
| الوصف: | A convenient and robust method for the preparation of new CF3-containing 2-quinolones has been developed via a Rh(III)-catalyzed C–H activation/Lossen rearrangement/annulation cascade of N-pivaloyloxy-arylamides with internal alkynes bearing an α-CF3-α-amino acid moiety on the triple bond. This work expands the scope of valuable products that are available through C–H activation/annulation reactions of arylamides in organic synthesis. |
| تدمد: | 1477-0539 1477-0520 |
| DOI: | 10.1039/d1ob01711j |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6977f621392a0fe05d44b1eb07492035 https://doi.org/10.1039/d1ob01711j |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....6977f621392a0fe05d44b1eb07492035 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14770539 14770520 |
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| DOI: | 10.1039/d1ob01711j |