The Sensitivity and Specificity of Touch Preparation for Rapid Diagnosis of Invasive Fungal Sinusitis: A Pilot Study
| العنوان: | The Sensitivity and Specificity of Touch Preparation for Rapid Diagnosis of Invasive Fungal Sinusitis: A Pilot Study |
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| المؤلفون: | Theodore A. Schuman, Jorge A. Almenara, Celeste N. Powers, Josephine H. Nguyen, Joshua C. Yelverton |
| المصدر: | Ear, Nose & Throat Journal. 100:55-59 |
| بيانات النشر: | SAGE Publications, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Adolescent, medicine.medical_treatment, Fulminant, Pilot Projects, Nose, Sensitivity and Specificity, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Predictive Value of Tests, Chart review, medicine, Humans, 030212 general & internal medicine, Sinusitis, Mycological Typing Techniques, 030223 otorhinolaryngology, Aged, Retrospective Studies, Debridement, Invasive fungal sinusitis, business.industry, Middle Aged, Predictive value, Confidence interval, Surgery, Otorhinolaryngology, Touch, Female, Touch Preparation, business, Invasive Fungal Infections |
| الوصف: | Invasive fungal sinusitis is a morbid pathology that typically affects immunocompromised patients and may quickly progress to fulminant disease. The purpose of this study was to measure the sensitivity and specificity of touch preparation of nasal debridement specimens as a rapid diagnostic tool for invasive fungal sinusitis. A retrospective chart review was performed of 22 patients undergoing nasal debridement due to suspicion for invasive fungal sinusitis over a 10-year period. Thirteen patients had touch preparation of nasal specimens followed by routine histologic processing; 2 of these patients underwent two and 1 patient had three separate debridements, for a total of 17 touch preparations performed. The sensitivity and specificity of touch preparation were calculated by correlating the initial results with the presence of fungal invasion on final pathologic analysis. The sensitivity of touch preparation was 56% (95% confidence interval [CI]: 0.23 to 0.85), specificity was 100% (95% CI: 0.60 to 1.00), positive predictive value was 100% (95% CI: 0.46 to 1.00), and negative predictive value was 67% (95% CI: 0.35 to 0.89). This procedure may be a useful adjunct in situations requiring rapid diagnosis of invasive fungal sinusitis but should not be used as the sole criterion for determining the need for surgical intervention. |
| تدمد: | 1942-7522 0145-5613 |
| DOI: | 10.1177/0145561319840853 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696c993e2f4fa1941dda43f0cf38e60c https://doi.org/10.1177/0145561319840853 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....696c993e2f4fa1941dda43f0cf38e60c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19427522 01455613 |
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| DOI: | 10.1177/0145561319840853 |