Soybean Isoflavones Reduce Postmenopausal Bone Resorption in Female Japanese Immigrants in Brazil: A Ten-Week Study
| العنوان: | Soybean Isoflavones Reduce Postmenopausal Bone Resorption in Female Japanese Immigrants in Brazil: A Ten-Week Study |
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| المؤلفون: | Kei-ich Honda, Takanori Teramoto, Yukio Yamori, Yukio Moriguchi, Yutaka Fukui, Kazuhiko Taira, Emílio Hideyuki Moriguchi, Yasuo Nara, Masakazu Fukui, Ayako Miura |
| المصدر: | Journal of the American College of Nutrition. 21:560-563 |
| بيانات النشر: | Informa UK Limited, 2002. |
| سنة النشر: | 2002 |
| مصطلحات موضوعية: | medicine.medical_specialty, Deoxypyridinoline, Osteoporosis, Medicine (miscellaneous), Urine, Bone and Bones, Bone resorption, Excretion, chemistry.chemical_compound, Double-Blind Method, Japan, Bone Density, Internal medicine, Humans, Medicine, Bone Resorption, Osteoporosis, Postmenopausal, Nutrition and Dietetics, business.industry, Middle Aged, Isoflavones, medicine.disease, Resorption, Postmenopause, Endocrinology, chemistry, Plant protein, Female, Soybeans, business, Biomarkers, Brazil |
| الوصف: | Some human studies and animal models of experimental osteoporosis have shown that soy isoflavones may be effective on bone health. In this study, we carried out an intervention study to explore the effects of dietary isoflavone on bone metabolism.Forty healthy female postmenopausal Japanese immigrants living in Brazil were divided into two groups: isoflavone-administered (n = 20) or placebo (n = 20). Subjects in the isoflavone-administered group ingested 37.3 mg per day for 10 weeks. The collection of 24-hour urine and the measurement of bone stiffness were performed at 0 and 10 weeks. Urinary excretion of isoflavones and bone resorption markers were analyzed.Urinary isoflavone excretion in the isoflavone-administered group was significantly increased at weeks 3 and 10. Urinary excretion of bone resorption markers was reduced in the isoflavone-administered group, while the placebo group did not show any significant reduction. Differences in levels of urinary isoflavones and bone resorption markers between the two groups were significant.This study demonstrated that the bone resorption was associated with the intake of soy isoflavones in postmenopausal women, and continuous dietary intake of isoflavone may inhibit postmenopausal osteoporosis. |
| تدمد: | 1541-1087 0731-5724 |
| DOI: | 10.1080/07315724.2002.10719255 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ea89663d63c17cbc9186800f84192f https://doi.org/10.1080/07315724.2002.10719255 |
| رقم الانضمام: | edsair.doi.dedup.....67ea89663d63c17cbc9186800f84192f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15411087 07315724 |
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| DOI: | 10.1080/07315724.2002.10719255 |