Histopathological Analysis of False-positive Lesions in mpMRI/TRUS Fusion Prostate Biopsy
| العنوان: | Histopathological Analysis of False-positive Lesions in mpMRI/TRUS Fusion Prostate Biopsy |
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| المؤلفون: | RYOKEN YAMANAKA, YOHEI SEKINO, TAKASHI BABASAKI, KOHEI KOBATAKE, HIROYUKI KITANO, KENICHIRO IKEDA, KEISUKE GOTO, TETSUTARO HAYASHI, JUN TEISHIMA, YUKIO TAKESHIMA, YUKIKO HONDA, KAZUO AWAI, NOBUYUKI HINATA |
| المصدر: | In Vivo |
| بيانات النشر: | Anticancer Research USA Inc., 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Image-Guided Biopsy, Male, Pharmacology, Cancer Research, Biopsy, Prostate, Prostatic Neoplasms, Magnetic Resonance Imaging, General Biochemistry, Genetics and Molecular Biology, Humans, Multiparametric Magnetic Resonance Imaging, Research Article, Retrospective Studies, Ultrasonography |
| الوصف: | Background/Aim: Multi-parametric magnetic resonance imaging (mpMRI)/ultrasonography fusion prostate biopsy (FB) is a more accurate method of diagnosis than conventional prostate biopsy, but false-positive lesions still exist. Limited studies have examined the cause of false-positive lesions by histological analysis. Patients and Methods: We examined 322 patients who underwent mpMRI/transrectal ultrasonography (TRUS) FB. We classified prostate imaging-recording and data system (PI-RADS) 3 and PI-RADS 4-5 as low PI-RADS lesions and high PI-RADS lesions, respectively. In total, 105 lesions were identified as false-positive lesions. We performed histological analysis of atrophy, hyperplasia, and lymphocyte infiltration in these lesions, comparing low PI-RADS lesions and high PI-RADS lesions. Results: The frequencies of prostate hyperplasia and lymphocyte infiltration were higher in high PI-RADS lesions than in low PI-RADS lesions (p=0.028 and 0.024, respectively). There was no significant difference regarding atrophy (p=0.295). Conclusion: Histopathological change may be one of the reasons for false-positive lesions. |
| تدمد: | 1791-7549 0258-851X |
| DOI: | 10.21873/invivo.12730 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c0237e33b493901cfc5f5781945dc7 https://doi.org/10.21873/invivo.12730 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....67c0237e33b493901cfc5f5781945dc7 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17917549 0258851X |
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| DOI: | 10.21873/invivo.12730 |