Combined effects of cognitive impairment and pre-frailty on future frailty and death in older Mexican Americans
| العنوان: | Combined effects of cognitive impairment and pre-frailty on future frailty and death in older Mexican Americans |
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| المؤلفون: | Kyriakos S. Markides, Kenneth J. Ottenbacher, Brian Downer, Mukaila A. Raji, Bret T. Howrey, Soham Al Snih |
| المصدر: | Aging Ment Health |
| بيانات النشر: | Informa UK Limited, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, Gerontology, health care facilities, manpower, and services, Frail Elderly, Comorbidity, Mexican americans, Health outcomes, Risk Assessment, Article, Pre frailty, 03 medical and health sciences, 0302 clinical medicine, Mexican Americans, Humans, Medicine, Cognitive Dysfunction, Longitudinal Studies, Cognitive skill, Mortality, Cognitive impairment, Aged, Aged, 80 and over, Frailty, 030214 geriatrics, business.industry, Cognition, United States, Psychiatry and Mental health, Female, Functional status, Geriatrics and Gerontology, Pshychiatric Mental Health, business, human activities, 030217 neurology & neurosurgery |
| الوصف: | OBJECTIVES: Impaired cognition and pre-frailty are associated with poor health outcomes. However, research has not examined the combined impact of cognitive impairment and pre-frailty on future frailty and mortality among older Mexican Americans. METHODS: Data for this analysis came from the 2006–07 and 2010–11 waves of the Hispanic EPESE. The final sample included 639 Mexican Americans aged ≥77 years who were non-frail or pre-frail in 2006–07. Frailty measure included weight loss, exhaustion, weakness, and slow walking speed. Participants were classified as non-frail (0 criteria) and pre-frail (1 criterion) at baseline. Cognitive impairment was defined as < 21 points on the MMSE. At baseline, participants were grouped as: cognitively intact non-frail, cognitively intact pre-frail, cognitively impaired non-frail, and cognitively impaired pre-frail. Logistic and hazard regression models were used to evaluate the odds of being frail in 2010–11 and risk for 10-year mortality. RESULTS: Cognitively impaired pre-frail participants were more likely to become frail (OR=4.82, 95% CI=2.02–11.42) and deceased (HR=1.99, 95% CI=1.42–2.78). Cognitively impaired non-frail participants had significantly higher risk for mortality (HR=1.55, 95% CI=1.12–2.19) but not frailty (OR=1.29, 95% CI=0.50–3.11). Being cognitively intact and pre-frail at baseline was not significantly associated with being frail at follow-up (OR=1.62, 95% CI=0.83–3.19) or mortality (HR=1.29, 95% CI=0.97–1.71). CONCLUSIONS: Comorbid cognitive impairment and pre-frailty is associated with future frailty and mortality in older Mexican Americans. Screening for cognitive impairment may be effective for identifying pre-frail Mexican Americans who are at the highest risk of frailty and mortality. |
| تدمد: | 1364-6915 1360-7863 |
| DOI: | 10.1080/13607863.2018.1493719 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6409629c98c1e293c758d990198d2fc3 https://doi.org/10.1080/13607863.2018.1493719 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....6409629c98c1e293c758d990198d2fc3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13646915 13607863 |
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| DOI: | 10.1080/13607863.2018.1493719 |