Chiral Monodentate Trialkylphosphines Based on the Phospholane Architecture
| العنوان: | Chiral Monodentate Trialkylphosphines Based on the Phospholane Architecture |
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| المؤلفون: | Tanguy Saget, Nicolai Cramer, Pavel A. Donets |
| المصدر: | Organometallics |
| بيانات النشر: | American Chemical Society (ACS), 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Steric effects, Denticity, 010405 organic chemistry, Stereochemistry, Organic Chemistry, chemistry.chemical_element, Tricyclohexylphosphine, 010402 general chemistry, 01 natural sciences, 0104 chemical sciences, Catalysis, Inorganic Chemistry, chemistry.chemical_compound, Nickel, chemistry, Physical and Theoretical Chemistry, Phosphine, Palladium, Electronic properties |
| الوصف: | The development of efficient chiral monodentate phosphine ligands lags behind that of the bidentate congeners. This holds especially true for highly electron rich chiral phosphine analogues able to replace the ubiquitous tricyclohexylphosphine and tri-tert-butylphosphine in catalytic asymmetric transformations. We present a convenient and modular synthesis of a set of chiral monodentate ligands with different steric demands based on the popular phospholane scaffold. Their steric and electronic properties were determined by their corresponding nickel and palladium complexes. They represent good mimics of the popular tricyclohexylphosphine and tri-tert-butylphosphine ligands. Their potential was subsequently evaluated in palladium-catalyzed asymmetric C(sp(3))-H functionalization leading to indolines. |
| تدمد: | 1520-6041 0276-7333 |
| DOI: | 10.1021/om3008772 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e58549933e128197c6d13a60d500e6b https://doi.org/10.1021/om3008772 |
| Rights: | RESTRICTED |
| رقم الانضمام: | edsair.doi.dedup.....5e58549933e128197c6d13a60d500e6b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15206041 02767333 |
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| DOI: | 10.1021/om3008772 |