Recommended vaccinations for asplenic and hyposplenic adult patients
| العنوان: | Recommended vaccinations for asplenic and hyposplenic adult patients |
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| المؤلفون: | Sara Boccalini, Alessandro Bartoloni, Angela Bechini, Maddalena Grazzini, Maria Teresa Mechi, Lea Magistri, Carlo Bonito, Paola Zini, F Niccolini, Simonetta Baretti, Maria Grazia Santini, Diana Paolini, Paolo Bonanni, Filippo Bartalesi, Giuditta Niccolai, Ornella Varone, Maria Beatrice Pulci |
| المصدر: | Human Vaccines & Immunotherapeutics |
| بيانات النشر: | Taylor & Francis, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | 0301 basic medicine, Adult, Pediatrics, medicine.medical_specialty, medicine.medical_treatment, Fulminant, 030106 microbiology, Immunology, Splenectomy, Review, asplenic, vaccinations, xx, infectious diseases, splenectomy, 03 medical and health sciences, 0302 clinical medicine, prevention, medicine, Disease Transmission, Infectious, Immunology and Allergy, Humans, 030212 general & internal medicine, Encapsulated bacteria, Splenic Diseases, Pharmacology, Vaccines, Adult patients, business.industry, Vaccination, Immunologic Deficiency Syndromes, medicine.disease, hyposplenic, Orthomyxoviridae, recommendations, Splenic disease, business, Sudden onset |
| الوصف: | Asplenic or hyposplenic (AH) individuals are particularly vulnerable to invasive infections caused by encapsulated bacteria. Such infections have often a sudden onset and a fulminant course. Infectious diseases (IDs) incidence in AH subjects can be reduced by preventive measures such as vaccination. The aim of our work is to provide updated recommendations on prevention of infectious diseases in AH adult patients, and to supply a useful and practical tool to healthcare workers for the management of these subjects, in hospital setting and in outpatients consultation. A systematic literature review on evidence based measures for the prevention of IDs in adult AH patients was performed in 2015. Updated recommendations on available vaccines were consequently provided. Vaccinations against S. pneumoniae, N. meningitidis, H. influenzae type b and influenza virus are strongly recommended and should be administered at least 2 weeks before surgery in elective cases or at least 2 weeks after the surgical intervention in emergency cases. In subjects without evidence of immunity, 2 doses of live attenuated vaccines against measles-mumps-rubella and varicella should be administered 4–8 weeks apart from each other; a booster dose of tetanus, diphtheria and pertussis vaccine should be administered also to subjects fully vaccinated, and a 3-dose primary vaccination series is recommended in AH subjects with unknown or incomplete vaccination series (as in healthy people). Evidence based prevention data support the above recommendations to reduce the risk of infection in AH individuals. |
| اللغة: | English |
| تدمد: | 2164-554X 2164-5515 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d7ef5644e241af39e1763ccbaaf75f1 http://europepmc.org/articles/PMC5328222 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....5d7ef5644e241af39e1763ccbaaf75f1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 2164554X 21645515 |
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