Development and Characterization of Novel Biopolymer Derived from Abelmoschus esculentus L. Extract and Its Antidiabetic Potential
| العنوان: | Development and Characterization of Novel Biopolymer Derived from Abelmoschus esculentus L. Extract and Its Antidiabetic Potential |
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| المؤلفون: | Eyad Alshammari, Khalid Mehmood, Mohd Adnan, Jerold C. Alcantara, Mushtaq Ahmad Khan, Syed Amir Ashraf, Nagat Elzein Eltoum, Abd Elmoneim O. Elkhalifa, Amir Mahgoub Awadelkareem |
| المصدر: | Molecules, Vol 26, Iss 3609, p 3609 (2021) Molecules Volume 26 Issue 12 |
| بيانات النشر: | MDPI AG, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Potassium, Sodium, α-amylase activity, Pharmaceutical Science, chemistry.chemical_element, Organic chemistry, 02 engineering and technology, okra polysaccharides, engineering.material, Polysaccharide, Article, Antioxidants, Analytical Chemistry, 03 medical and health sciences, Plant Mucilage, Nutraceutical, Biopolymers, QD241-441, Abelmoschus, Polysaccharides, biopolymer, Drug Discovery, Spectroscopy, Fourier Transform Infrared, Hypoglycemic Agents, Food science, Physical and Theoretical Chemistry, Solubility, 030304 developmental biology, chemistry.chemical_classification, nutraceuticals, 0303 health sciences, biology, α-glucosidase activity, Plant Extracts, okra mucilage, alpha-Glucosidases, 021001 nanoscience & nanotechnology, biology.organism_classification, chemistry, Mucilage, antidiabetic activity, Chemistry (miscellaneous), Dietary Supplements, engineering, Molecular Medicine, Biopolymer, alpha-Amylases, 0210 nano-technology |
| الوصف: | Abelmoschus esculentus (Okra) is an important vegetable crop, widely cultivated around the world due to its high nutritional significance along with several health benefits. Different parts of okra including its mucilage have been currently studied for its role in various therapeutic applications. Therefore, we aimed to develop and characterize the okra mucilage biopolymer (OMB) for its physicochemical properties as well as to evaluate its in vitro antidiabetic activity. The characterization of OMB using Fourier-transform infrared spectroscopy (FT-IR) revealed that okra mucilage containing polysaccharides lies in the bandwidth of 3279 and 1030 cm−1, which constitutes the fingerprint region of the spectrum. In addition, physicochemical parameters such as percentage yield, percentage solubility, and swelling index were found to be 2.66%, 96.9%, and 5, respectively. A mineral analysis of newly developed biopolymers showed a substantial amount of calcium (412 mg/100 g), potassium (418 mg/100 g), phosphorus (60 mg/100 g), iron (47 mg/100 g), zinc (16 mg/100 g), and sodium (9 mg/100 g). The significant antidiabetic potential of OMB was demonstrated using α-amylase and α-glucosidase enzyme inhibitory assay. Further investigations are required to explore the newly developed biopolymer for its toxicity, efficacy, and its possible utilization in food, nutraceutical, as well as pharmaceutical industries. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1420-3049 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cffeae46e2433dfbf42db362c19cdf5 https://www.mdpi.com/1420-3049/26/12/3609 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....5cffeae46e2433dfbf42db362c19cdf5 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14203049 |
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